Dr. Marianne Fleuti

e-mail: marianne.fleuti@uochb.cas.cz
phone: +420 221951331


Born 01. 09. 1986 in Brugg AG (Switzerland).

Scientific CV:
2007-2012 undergraduate study, ETH Zurich, B. Sc. degree
2009-2014 teaching assistant, ETH Zurich, Lecture and Lab Course "Chemistry for Biology, Pharmaceutical & Health Sciences"
2012-2015 graduate study, ETH Zurich, M. Sc. degree (supervisor Prof. Dr. F. Diederich)
2015 internship, Institute of Chemical Process Fundamentals of AVČR (project supervisor Dr. J. Storch)
since 2016 PhD. study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)

List of publications:

4.	Fleuti, M.; Sanchez-Quirante, T.; Poštová Slavĕtínská, L.; Tloušťová, E.; Tichý, M.; Gurská, S.; Džubák, P.; Hajdúch, M. and Hocek, M.: "Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides" ACS Omega 2024, 9(18), 20557-20570.
3.	Yang, Ch.; Slavĕtínská Poštová, L.; Fleuti, M.; Klepetářová, B.; Tichý, M.; Gurská, S.; Pavliš, P.; Džubák, P.; Hajdúch, M. and Hocek, M.: "Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling" J. Am. Chem. Soc. 2022, 144 (42), 19437-19446.
2.	Fleuti, M.; Bártová, K.; Poštová Slavetínská, L.; Tlouštová, E.; Tichý, M.; Gurská, S.; Pavliš, P.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides" J. Org. Chem. 2020, 85, 10539-10551.
1.	Giroud, M.; Ivkovic, J.; Martignoni, M.; Fleuti, M.; Trapp, N.; Haap, W.; Kuglstatter, A.; Benz, J.; Kuhn, B.; Schirmeister, T.; Diederich, F.: "Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: Amide···Heteroarene ?-Stacking Interactions and Chalcogen Bonding in the S3 Pocket" ChemMedChem 2017, 12, 257-270.