Hosek Research Team
Hosek Research Team
Hocek Research Team

Dr. Dmytro Dziuba

Dmytro Dziuba

e-mail: dmytro.dziuba@uochb.cas.cz
phone: +420 220183344

Born 8. 9. 1986 Ukraine.

Scientific CV:
2003-2007 Undergraduate study Kiev National Taras Shevchenko University, Ukraine, BSc. degree - specialization: organic chemistry (supervisor: Dr. Olga V. Khilya)
2007-2008 Undergraduate study Kiev National Taras Shevchenko University, Ukraine, MSc. degree - specialization: organic chemistry & chemistry of natural products (supervisor: Dr. Olga V. Khilya)
2008-2012 Ph.D. study Institute of Chemistry, Nice Sophia Antipolis University, France (supervisor Prof. Alain Burger and Dr. Rachid Benhida)
2012-2016 Postdoctoral position at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic
since 2016 Postdoctoral position at the EMBL Heidelberg as an EIPOD postdoctoral fellow.

List of publications:

11. Güixens-Gallardo, P.; Zawada, Z.; Matyašovský, J.; Dziuba, D.; Pohl, R.; Kraus, T.; Hocek.: "Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in cellulo Incorporation to DNA, Imaging and Flow Cytometry" Bioconjug. Chem. 2018, 29, 3906 – 3912.
10. Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M.: "Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions" Chem. Sci. 2016, 7, 5775 - 5785.
9. Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M.: "Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurineBases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions" Synthesis 2016, 48, 1029 – 1045.
8. Dziuba, D.; Jurkiewicz, P.; Cebecauer, M.; Hof, M.; Hocek, M.: "A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy" Angew. Chem. Int. Ed. 2016, 55, 174 – 178.
7. Barthes, N. P. F.; Karpenko, I. A.; Dziuba, D.; Spadafora, M.; Auffret, J.; Demchenko, A. P.; Mély, Y.; Benhida, R.; Michel, B. Y.; Burger, A.: "Development of environmentally sensitive fluorescent and dual emissive deoxyuridine analogues" RSC Adv.. 2015, 5, 33536 – 33545.
6. Dziuba, D.; Pohl, R.; Hocek, M.: "Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins" Chem. Commun. 2015, 51, 4880 – 4882.
5. Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction" Bioconjugate Chem. 2015, 26, 361 – 366.
4. Dziuba, D.; Pohl, R.; Hocek, M.: "Bodipy-labelled nucleoside triphosphates for polymerase synthesis of fluorescent DNA" Bioconjugate Chem. 2014, 25, 1984 – 1995.
3. Dziuba, D.; Karpenko, I. A.; Barthes, N. P. F.; Michel, B. Y.; Klymchenko, A. S.; Benhida, R.; Demchenko, A. P.; Mély, Y.; Burger, A.: "Rational Design of a Solvatochromic Fluorescent Uracil Analogue with a Dual-Band Ratiometric Response Based on 3-Hydroxychromone" Chem. Eur. J. 2014, 20, 1998–2009.
2. Dziuba, D.; Postupalenko, V.; Spadafora, M.; Klymchenko, A.; Guérineau, V.; Mély, Y.; Benhida, R.; Burger, A.: "A Universal Nucleoside with Strong Two-Band Switchable Fluorescence and Sensitivity to the Environment for Investigating DNA Interactions" J. Am. Chem. Soc. 2012, 134, 10209–10213.
1. Dziuba, D.; Benhida, R.; Burger, A.: "A Mild and Efficient Protocol for the Protection of 3-Hydroxychromones under Phase-Transfer Catalysis" Synthesis 2011, 18, 2159-2164.

Prize for the best poster at the first international conference on Fluorescent Biomolecules and their Building Blocks – Design and Applications (FB3), Göteborg, Sweden, July 2012

© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic