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2024
286. Gracias, F.; Pohl, R.; Sykorova, V.; Hocek, M.: "Bacteriophage-related epigenetic natural and non-natural pyrimidine nucleotides and their influence on transcription with T7 RNA polymerase" Commun. Chem. 2024, 7, 256.
Chemical biology of base-modified nucleic acids
285. Krömer, M.; Poštová Slavĕtínská, L. and Hocek, M.: "Glyco-DNA: Enzymatic Synthesis of Base-Modified and Hypermodified DNA Displaying up to Four Different Monosaccharide Units in the Major Groove" Chem. Eur. J. 2024, e202402318.
Chemical biology of base-modified nucleic acids
284. Spampinato, A.; Leone, D.-L.; Pohl, R.; Tarábek, J.; Šoltysová, M.; Polák, M.; Kádek, A.; Sýkorová, V.; Řezáčová, P. and Hocek, M.: "ABNOH-Linked Nucleotides and DNA for Bioconjugation and Cross-linking with Tryptophan-Containing Peptides and Proteins" Chem. Eur. J. 2024, e202402151.
Chemical biology of base-modified nucleic acids
283. Brunderová, M.; Havlíček, V.; Matyašovský, J.; Pohl, R.; Poštová Slavĕtínská, L.; Krömer, M. and Hocek, M.: "Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases" Nat. Commun. 2024, 15, 3054.
Chemical biology of base-modified nucleic acids
282. Fleuti, M.; Sanchez-Quirante, T.; Poštová Slavĕtínská, L.; Tloušťová, E.; Tichý, M.; Gurská, S.; Džubák, P.; Hajdúch, M. and Hocek, M.: "Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides" ACS Omega 2024, 9(18), 20557-20570.
Chemical biology of base-modified nucleic acids

2023
281. Kuprikova, N.; Ondruš, M.; Bednárová, L.; Riopedre Fernández, M.; Poštová Slavĕtínská, L.; Sýkorová, V.; Hocek, M.: "Superanionic DNA. Enzymatic Synthesis of Hypermodified DNA Bearing Four Different Anionic Substituents at all Four Nucleobases" Nucleic Acids Res. 2023, 51 (21), 11428-11438.
Chemical biology of base-modified nucleic acids
280. Jestřábová, I.; Poštová Slavĕtínská, L.; Hocek, M.: "Arylethynyl- or Alkynyl-Linked Pyrimidine and 7-Deazapurine 2'-Deoxyribonucleoside 3'-Phosphoramidites for Chemical Synthesis of Hypermodified Hydrophobic Oligonucleotides" ACS Omega 2023, 8 (42), 39447-39453.
Chemical biology of base-modified nucleic acids
279. Yang, C.; Tichý, M.; Poštová Slavĕtínská, L.; Vaiedelich, E.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Biological Profiling of Benzofuro-Fused 7-Deazapurine Nucleosides" Eur. J. Org. Chem. 2023, e202300723.
Chemical biology of base-modified nucleic acids
278. Kodr, D.; Ortiz, M.; Sýkorová, V.; Yenice, C. P.; Lesnikowski, Z. J.; O’Sullivan, C. K.; Hocek, M.: "Normalized Multipotential Redox Coding of DNA Bases for Determination of Total Nucleotide Composition" Anal. Chem. 2023, 95, 12586-12589.
Chemical biology of base-modified nucleic acids
277. Kuba, M.; Khorosyy, P.; Lepšík, M.; Kužmová, E.; Kodr, D.; Kraus, T.; Hocek, M.: "Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides" Angew. Chem. Int. Ed. 2023, 62, e202307548.
Chemical biology of base-modified nucleic acids
276. Ortiz, M.; Jauset-Rubio, M.; Trummer, O.; Foessl, I.; Kodr, D.; Acero, J. L.; Botero, M. L.; Biggs, P.; Lenartowicz, D.; Trajanoska, K.; Rivadeneira, F.; Hocek, M.; Obermayer-Pietsch, B.; O’Sullivan, C. K.: "Generic Platform for the Multiplexed Targeted Electrochemical Detection of Osteoporosis-Associated Single Nucleotide Polymorphisms Using Recombinase Polymerase Solid-Phase Primer Elongation and Ferrocene-Modified Nucleoside Triphosphates" ACS Cent. Sci. 2023, 9, 1591-1602.
Chemical biology of base-modified nucleic acids
275. Mulholland, C.; Jestřábová, I.; Sett, A.; Ondruš, M.; Sýkorová, V.; Manzanares, C. L.; Šimoncík, O.; Muller, P. and Hocek, M.: "The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70" Commun. Chem. 2023, 6, 65.
Chemical biology of base-modified nucleic acids
274. Kodr, D.; Kužmová, E.; Pohl, R.; Kraus, T. and Hocek, M.: "Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency" Chem. Sci. 2023, 14, 4059-4069.
Chemical biology of base-modified nucleic acids
273. Spampinato, A.; Kužmová, E.; Pohl, R.; Sýkorová, V.; Vrábel, M.; Kraus, T. and Hocek, M.: "trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging" Bioconjugate Chem. 2023, 34(4), 772-780.
Chemical biology of base-modified nucleic acids
272. Brunderová, M.; Krömer, M.; Vlková, M. and Hocek, M.: "Chloroacetamide-Modified Nucleotide and RNA for Bioconjugations and Cross-Linking with RNA-Binding Proteins" Angew. Chem. Int. Ed. 2023, 62, e202213764.
Chemical biology of base-modified nucleic acids
271. Kuba, M.; Pohl, R.; Kraus, T. and Hocek, M.: "Nucleotides Bearing Red Viscosity-Sensitive Dimethoxy-Bodipy Fluorophore for Enzymatic Incorporation and DNA Labeling" Bioconjugate Chem. 2023, 34 (1), 133-139.
Chemical biology of base-modified nucleic acids

2022
270. Yang, Ch.; Slavĕtínská Poštová, L.; Fleuti, M.; Klepetářová, B.; Tichý, M.; Gurská, S.; Pavliš, P.; Džubák, P.; Hajdúch, M. and Hocek, M.: "Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling" J. Am. Chem. Soc. 2022, 144 (42), 19437-19446.
Chemical biology of base-modified nucleic acids
269. Vavřina, Z.; Perlíková, P.; Milisavljevic, N.; Chevrier, F.; Smola, M.; Smith, J.; Dejmek, M.; Havlíček, V.; Budešínský, M.; Liboska, R.; Vaneková, L.; Brynda, J.; Bouřa, E.; Řezáčová, P.; Hocek, M. and Birkuš,G.: "Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists" J. Med. Chem. 2022, 65 (20), 14082-14103.
Chemical biology of base-modified nucleic acids
268. Ondruš, M.; Sýkorová, V.; Hocek, M.: "Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates" Chem. Commun. 2022, 58, 11248-11251.
Chemical biology of base-modified nucleic acids
267. Gracias, F.; Ruiz-Larrabeiti, O.; Vaňková Hausnerová, V.; Pohl, R.; Klepetářová, B.; Sýkorová, V.; Krásný, L.; Hocek, M.: "Homologues of epigenetic pyrimidines: 5-alkyl-, 5-hydroxyalkyl and 5-acyluracil and -cytosine nucleotides: synthesis, enzymatic incorporation into DNA and effect on transcription with bacterial RNA polymerase" RSC Chem. Biol. 2022, 3, 1069-1075.
Chemical biology of base-modified nucleic acids
266. Pospíšil, Š.; Panattoni, A.; Gracias, F.; Sýkorová, V.; Hausnerová, V. V.; Vítovská, D.; Šanderová, H.; Krásný, L.; Hocek, M.: "Epigenetic Pyrimidine Nucleotides in Competition with Natural dNTPs as Substrates for Diverse DNA Polymerases" ACS Chem. Biol. 2022, 17 (10), 2781-2788.
Chemical biology of base-modified nucleic acids
265. Chakrapani, A.; Ruiz-Larrabeiti, O.; Pohl, R.; Svoboda, M.; Krásný, L.; Hocek, M.: "Glucosylated 5-hydroxymethylpyrimidines as epigenetic DNA bases regulating transcription and restriction cleavage" Chem. Eur. J. 2022, 28, e202200911.
Chemical biology of base-modified nucleic acids
264. Leone, D.-L.; Pohl, R.; Hubálek, M.; Kaderábková, M.; Krömer, M.; Sýkorová, V.; Hocek, M.: "Glyoxal-Linked Nucleotides and DNA for Bioconjugations and Cross-Linking with Arginine-Containing Peptides and Proteins" Chem. Eur. J. 2022, 28, e202104208.
Chemical biology of base-modified nucleic acids
263. Ortiz, M.; Jauset-Rubio, M.; Kodr, D.; Simonova, A.; Hocek, M.; O´Sullivan, C. K.: "Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms" Biosens. Bioelectron. 2022, 198, 113825.
Chemical biology of base-modified nucleic acids
262. Sýkorová, V.; Tichý, M.; Hocek, M.: "Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7-Deazapurine Nucleobases and Their Post-synthetic Modifications through the Suzuki-Miyaura Cross-Coupling Reactions" ChemBioChem 2022, 23, e202100608.
Chemical biology of base-modified nucleic acids

2021
261. Ortiz, M.; Jauset-Rubio, M.; Skouridou, V.; Machado, D.; Viveiros, M.; Clark, T. G.; Simonova, A.; Kodr, D.; Hocek, M.; O´Sullivan, C. K.: "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked RedoxLabeled Nucleotides" ACS Sens. 2021, 6, 4398-4407.
Chemical biology of base-modified nucleic acids
260. Matyašovský, J.; Tack, L.; Palágyi, A.; Kuba, M.; Pohl, R.; Kraus, T.; Güixens-Gallardo, P.; Hocek, M.: "Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein–DNA binding" Org. Biomol. Chem. 2021, 19, 9966-9974.
Chemical biology of base-modified nucleic acids
259. Leone, D.-L.; Hubálek, M.; Pohl, R.; Sýkorová, V.; Hocek, M.: "1,3-Diketone-Modified Nucleotides and DNA for Cross-Linking with Arginine-Containing Peptides and Proteins" Angew. Chem. Int. Ed. 2021, 60, 17383-17387.
Chemical biology of base-modified nucleic acids
258. Kodr, D.; Yenice, C. P.; Simonova, A.; Saftic, D. P.; Pohl, R.; Sýkorová, V.; Ortiz, M.; Havran, L.; Fojta, M.; Lesnikowski, Z. J.; O’Sullivan, C. K.; Hocek, M.: "Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing" J. Am. Chem. Soc. 2021, 143 (18), 7124-7134.
Chemical biology of base-modified nucleic acids
257. Perlíková, P.; Krajczyk, A.; Doleželová, E.; Slapnicková, M.; Milisavljevic, N.; Poštová Slavetínská, L.; Tlouštová, E.; Gurská, S.; Džubák, P; Hajdúch, M.; Zíková, A.; Hocek, M.: "Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides" ACS Infect. Dis. 2021, 7 (4), 917-926.
This publication was featured on a cover:

Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
256. Güixens-Gallardo, P.; Hocek, M.: "Acetophenyl-thienyl-aniline-linked nucleotide for construction of solvatochromic fluorescence light-up DNA probes sensing protein-DNA interactions" Chem. Eur. J. 2021, 27, 7090-7093.
Chemical biology of base-modified nucleic acids
255. Nguyen, V. H.; Tichý, M.; Rožánková, S.; Pohl, R.; Downey, M. A.; Doleželová, E.; Tlouštová, E.; Slapnicková, M.; Zíková, A.; Hocek, M.: "Synthesis and Anti-trypanosomal Activity of 3'-Fluororibonucleosides Derived from 7-Deazapurine Nucleosides" Bioorg. Med. Chem. Lett. 2021, 40, 127957.
Chemical biology of base-modified nucleic acids
254. Magrińá, I.; Ortiz, M.; Simonova, A.; Hocek, M.; O'Sullivan, C. K.; Forster, R. J.: "Ferrocene Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics" Langmuir 2021, 37 (11), 3359-3369.
Chemical biology of base-modified nucleic acids
253. Milisavljevic, N.; Konkolová, E.; Kozák, J.; Hodek, J.; Veselovská, L.; Sýkorová, V.; Cížek, K.; Pohl, R.; Eyer, L.; Svoboda, P.; Ružek, D.; Weber, J.; Nencka, R.; Boura, E.; Hocek, M.: "Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses" ACS Infect. Dis. 2021, 7 (2), 471-478.
Chemical biology of base-modified nucleic acids

2020
252. Ondruš, M.; Sýkorová, V.; Bednárová, L.; Pohl, R.; Hocek, M.: "Enzymatic Synthesis of Hypermodified DNA Polymers for Sequence-Specific Display of Four Different Hydrophobic Groups" Nucleic Acids Res. 2020, 48 (21), 11982-11993.
Chemical biology of base-modified nucleic acids
251. Chakrapani, A.; Vanková Hausnerová, V.; Ruiz-Larrabeiti, O.; Pohl, R.; Krásný, L.; Hocek, M.: "Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labelling of DNA" Org. Lett. 2020, 22, 9081-9085.
Chemical biology of base-modified nucleic acids
250. Veselovská, L.; Pohl, R.; Tlouštová, E.; Gurská, S.; B.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2',3':4,5]- and Pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidines" ACS Omega 2020, 5, 26278-26286.
Chemical biology of base-modified nucleic acids
249. Veselovská, L.; Kudlová, N.; Gurská, S.; Lišková, B.; Medvedíková, M.; Hodek, O.; Tlouštová, E.; Milisavljevic, N.; Tichý, M.; Perlíková, P.; Mertlíková-Kaiserová, H.; Trylcová, J.; Pohl, R.; Klepetárová, B.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides" Chem. Eur. J. 2020, 26, 13002-13015.
Chemical biology of base-modified nucleic acids
248. Fleuti, M.; Bártová, K.; Poštová Slavetínská, L.; Tlouštová, E.; Tichý, M.; Gurská, S.; Pavliš, P.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides" J. Org. Chem. 2020, 85, 10539-10551.
Chemical biology of base-modified nucleic acids
247. Kuba, M.; Kraus, T.; Pohl. R.; Hocek, M.: "Nucleotide bearing benzylidene-tetrahydroxanthylium near-IR fluorophore for sensing DNA replication, secondary structures and interactions" Chem. Eur. J. 2020, 26, 11950-11954.
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Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
246. Krömer, M.; Brunderová, M.; Ivancová, I.; Poštová Slavetínská, L.; Hocek, M.: "2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA bearing an Aldehyde Group in the Minor Groove" ChemPlusChem 2020, 85, 1164-1170.
Chemical biology of base-modified nucleic acids
245. Yang, C.; Pohl, R.; Tichý, M.; Gurská, S.; Pavliš, P.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides" J. Org. Chem. 2020, 85, 8085-8101.
Chemical biology of base-modified nucleic acids
244. Güixens-Gallardo, P.; Humpolíčková, J.; Miclea, S. P.; Pohl, R.; Kraus, T.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucloetide probes of hybridization and protein-DNA interactions" Org. Biomol. Chem. 2020, 18, 912-919.
Chemical biology of base-modified nucleic acids
243. Simonova, A.; Magriná, I.; Sýkorová, V.; Pohl, R.; Ortiz, M.; Havran, L.; Fojta, M.; O'Sullivan, C. K.; Hocek, M.: "Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labelling and Coding of Nucleotides and DNA" Chem. Eur. J. 2020, 26, 1286-1291.
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Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
242. Panattoni, A.; El-Sagheer, A. H.; Brown, T.; Kellett, A.; Hocek, M.: "Oxidative DNA Cleavage with Clip-Phenanthroline Triplex Forming Oligonucleotide Hybrids" ChemBioChem 2020, 21, 991-1000.
Chemical biology of base-modified nucleic acids
241. Havranová-Vidláková, P.; Krömer, M.; Sýkorová, V.; Trefulka, M.; Fojta, M.; Havran, L.; Hocek, M.: "Vicinal Diol-Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes" ChemBioChem 2020, 21, 171-180.
Chemical biology of base-modified nucleic acids
240. Matyašovský, J.; Hocek, M.: "2-Substituted 2'-Deoxyinosine 5'-Triphosphates as Substrates for Polymerase Synthesis of Minor-Groove-Modified DNA and Effects on Restriction Endonuclease Cleavage" Org. Biomol. Chem. 2020, 18, 255-262.
Chemical biology of base-modified nucleic acids

2019
239. Magriná, I.; Jauset-Rubio, M.; Ortiz, M.; Tomaso, H.; Simonova, A.; Hocek, M.; O'Sullivan, C. K.: "Duplex electrochemical DNA sensor to detect B.anthracis CAP and PAG DNA targets based on the incorporation of tailed primers and ferrocene labelled dATP" ACS Omega 2019, 4, 21900-21908.
Chemical biology of base-modified nucleic acids
238. Ivancová, I.; Pohl, R.; Hubálek, M.; Hocek, M.: "Squaramate-Modified Nucleotides and DNA for Specific Cross-Linking with Lysine-Containing Peptides and Proteins" Angew. Chem. Int. Ed. 2019, 58, 13345-13348.
Chemical biology of base-modified nucleic acids
237. Ivancová, I.; Leone, D.-L.; Hocek, M.: "Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking" Curr. Opin. Chem. Biol. 2019, 52, 136-144.
Chemical biology of base-modified nucleic acids
236. Hocek, M.: "Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein–DNA Binding and Transcription" Acc. Chem. Res. 2019, 52, 1730-1737.
Chemical biology of base-modified nucleic acids
235. Ménová, P.; Vrábel, M.; Cahová, H.; Hocek, M.: "Synthesis of base-modified dNTPs through cross-coupling reactions and their polymerase incorporation to DNA" (Book Chapter), in Non-Natural Nucleic Acids: Methods and Protocols, Methods in Molecular Biology (N. Shank ed.), Humana Press, New York, NY, 2019, vol. 1973, pp. 39-57.
Chemical biology of base-modified nucleic acids
234. Malnuit, V.; Smoleń, S.; Tichý, M.; Poštová Slavětínská, L.; Hocek, M.: "Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine" Eur. J. Org. Chem. 2019, 5409-5423.
Chemical biology of base-modified nucleic acids
233. Magriná, I.; Toldra, A.; Campas, M.; Ortiz, M.; Simonova, A.; Katakis, I.; Hocek, M.; O'Sullivan, C. K.: "Electrochemical genosensor for the direct detection of tailed PCR amplicons incorporating ferrocene labelled dATP" Biosens. Bioelectron. 2019, 134, 76-82.
Chemical biology of base-modified nucleic acids
232. Vaníková, Z.; Janoušková, M.; Kambová, M.; Krásný, L.; Hocek, M.: "Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA" Chem. Sci. 2019, 10, 3937-3942.
Chemical biology of base-modified nucleic acids
231. Hermanová, M.; Orság, P.; Balintová, J.; Hocek, M.; Fojta, M.: "Dual Redox Labeling of DNA as a Tool for Electrochemical Detection of p53 Protein-DNA Interactions" Anal. Chim. Acta 2019, 1050, 123-131.
Chemical biology of base-modified nucleic acids

2018
230. Güixens Gallardo, P.; Zawada, Z.; Matyašovský, J.; Dziuba, D.; Pohl, R.; Kraus, T.; Hocek, M.: "Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in cellulo Incorporation to DNA, Imaging and Flow Cytometry" Bioconjug. Chem. 2018, 29, 3906-3912.
Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
229. Tokarenko, A.; Lišková, B.; Smoleń, S.; Táborská, N.; Tichý, M.; Gurská, S.; Perlíková, P.; Frydrych, I.; Tloušťová, E.; Znojek, P.; Mertlíková-Keiserová, H.; Poštová Slavětínská, L.; Pohl, R.; Klepetářová, B.; Khalid, N.; Wenren, Y.; Laposa, R. R.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides" J. Med. Chem. 2018, 61, 9347-9359.
Chemical biology of base-modified nucleic acids
228. Kuba, M.; Pohl, R.; Hocek, M.: "Synthesis of 2'-deoxycytidine and its triphosphate bearing tryptophan-based imidazolinone fluorophore for environment sensitive fluorescent labelling of DNA" Tetrahedron 2018, 74, 6621-6629.
Chemical biology of base-modified nucleic acids
227. Matyašovský, J.; Pohl, R.; Hocek, M.: "2-Allyl- and -propargylamino-dATPs for site-specific enzymatic introduction of a single modification in minor groove of DNA" Chem. Eur. J. 2018, 24, 14938-14941.
Chemical biology of base-modified nucleic acids
226. Tichý, M.; Smoleń, S.; Deingruber, T.; Džubák, P.; Pohl, R.; Poštová Slavětínská, L.; Hajdúch, M.; Hocek, M.: "Thienopyrrolo[2, 3-d]pyrimidines, New Tricyclic Nucleobase Analogues: Synthesis and Biological Activities" ChemistrySelect 2018, 3, 9144-9149.
Chemical biology of base-modified nucleic acids
225. Milisavljevič, N.; Perlíková, P.; Pohl, R.; Hocek, M.: "Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates" Org. Biomol. Chem. 2018, 16, 5800-5807.
Chemical biology of base-modified nucleic acids
224. Panattoni, A.; Pohl, R.; Hocek, M.: "Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Post-Synthetic DNA Functionalization through Copper-Catalyzed Alkyne–Azide 1,3-Dipolar Cycloaddition" Org. Lett. 2018, 20, 3962 - 3965.
Chemical biology of base-modified nucleic acids
223. Boháčová, S.; Vaníková, Z.; Poštová Slavětínská, L.; Hocek, M.: "Protected 2'-deoxyribonucleoside triphosphate building blocks for photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA" Org. Biomol. Chem. 2018, 16, 5427-5432.
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Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
222. Krömer, M.; Bártová, K.; Raindlová, V.; Hocek, M.: "Synthesis of dihydroxyalkynyl and dihydroxyalkyl nucleotides as building blocks or precursors for introduction of diol or aldehyde functions to DNA for bioconjugations" Chem. Eur. J. 2018, 24, 11890-11894.
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Chemical biology of base-modified nucleic acids
Chemical biology of base-modified nucleic acids
221. Slavíčková, M.; Janoušková, M.; Šimonová, A.; Cahová, H.; Kambová, M.; Šanderová, H.; Krásný, L.; Hocek, M.: "Turning off transcription with bacterial RNA polymerase through CuAAC click reactions of DNA containing 5-ethynyluracil" Chem. Eur. J. 2018, 24, 8311 - 8314.
Chemical biology of base-modified nucleic acids
220. Ghosh, K.; Perlíková, P.; Havlíček, V.; Yang, C.; Pohl, R.; Tloušťová, E.; Hodek, J.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Isomeric Naphtho-Fused 7-Deazapurine Nucleosides and Nucleotides. Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids" Eur. J. Org. Chem. 2018, 5092-5108.
Chemical biology of base-modified nucleic acids
219. Vosáhlová, J.; Koláčná, L.; Daňhel, A.; Fischer, J.; Balintová, J.; Hocek, M.; Scwarzová-Pecková, K.; Fojta, M.: "Voltammetric and adsorption study of 4-nitrophenyl-triazole-labeled 2'-deoxycytidine and 7-deazaadenosine nucleosides at boron-doped diamond electrode" J. Electroanal. Chem. 2018, 821, 111 - 120.
Chemical biology of base-modified nucleic acids
218. Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M.: "C-H imidation of 7-deazapurines" ACS Omega 2018, 3, 4674 - 4678.
Chemical biology of base-modified nucleic acids
217. Boháčová, S.; Ludvíková, L.; Poštová Slavětínská, L.; Vaníková, Z.; Klán, P.; Hocek, M.: "Protected 5-(hydroxymethyl)uracil nucleotides bearing visible-light photocleavable groups as building blocks for polymerase synthesis of photocaged DNA" Org. Biomol. Chem. 2018, 16, 1527 - 1535.
Chemical biology of base-modified nucleic acids
216. Havranová-Vidláková, P.; Špaček, J.; Vítová, L.; Hermanová, M.; Daďová, J.; Raindlová, V.; Hocek, M.; Fojta, M.; Havran, L.: "Butylacrylate-nucleobase Conjugates as Targets for Two-step Redox Labeling of DNA with an Osmium Tetroxide Complex" Electroanalysis 2018, 30, 371 - 377.
Chemical biology of base-modified nucleic acids
215. Daňhel, A.; Trošanová, Z.; Balintová, J.; Simonova, A.; Pospíšil, L.; Cvačka, J.; Hocek, M.; Fojta, M.: "Electrochemical reduction of azidophenyl-deoxynucleoside conjugates at mercury surface" Electrochim. Acta 2018, 259, 377 - 385.
Chemical biology of base-modified nucleic acids

2017
214. Janoušková, M.; Vaníková, Z.; Nici, F.; Boháčová, S.; Vítovská, D.; Šanderová, H.; Hocek, M.; Krásný, L.: "5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase" Chem. Commun. 2017, 53, 13253 - 13255.
Chemical biology of base-modified nucleic acids
213. Olszewska, A.; Pohl, R.; Hocek, M.: "Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA–Protein Interactions by 19F NMR Spectroscopy" J. Org. Chem. 2017, 82, 11431 - 11439.
Chemical biology of base-modified nucleic acids
212. Balintová, J.; Simonova, A.; Białek-Pietras, M.; Olejniczak, A.; Lesnikowski, Z. J.; Hocek, M.: "Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA" Bioorg. Med. Chem. Lett. 2017, 27, 4786 - 4788.
Chemical biology of base-modified nucleic acids
211. Perlíková, P.; Hocek, M.: "Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides" Med. Res. Rev. 2017, 37, 1429 - 1460.
Chemical biology of base-modified nucleic acids
210. Sabat, N.; Smoleń, S.; Nauš, P.; Perlíková, P.; Cebová, M.; Poštová Slavětínská, L.; Hocek, M.: "Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines)" Synthesis 2017, 49, 4623 - 4650.
Chemical biology of base-modified nucleic acids
209. Konč, J.; Tichý, M.; Pohl, R.; Hodek, J.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity" Med. Chem. Commun. 2017, 8, 1856 - 1862.
Chemical biology of base-modified nucleic acids
208. Simonova, A.; Havran, L.; Pohl, R.; Fojta, M.; Hocek, M.: "Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA" Org. Biomol. Chem. 2017, 15, 6984 - 6996.
Chemical biology of base-modified nucleic acids
207. Downey, A. M.; Hocek, M.: "Strategies toward protecting group-free glycosylation through selective activation of the anomeric center" Beilstein J. Org. Chem. 2017, 13, 1239 - 1279.
Chemical biology of base-modified nucleic acids
206. Tichý, M.; Smoleń, S.; Tloušťová, E.; Pohl, R.; Oždian, T.; Hejtmánková, K.; Lišková, B.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides" J. Med. Chem. 2017, 60, 2411 - 2424.
Chemical biology of base-modified nucleic acids
205. Downey, A. M.; Pohl, R.; Roithová, J.; Hocek, M.: "Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism" Chem. Eur. J. 2017, 23, 3910 - 3917.
Chemical biology of base-modified nucleic acids

2016
204. Matyašovský, J.; Perlíková, P.; Malnuit, V.; Pohl, R.; Hocek, M.: "2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove" Angew. Chem. Int. Ed. 2016, 55, 15856 - 15859.
Chemical biology of base-modified nucleic acids
203. Slavíčková, M.; Pohl, R.; Hocek, M.: "Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA" J. Org. Chem. 2016, 81, 11115 - 11125.
Chemical biology of base-modified nucleic acids
202. Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M.: "5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs" ACS Chem. Biol. 2016, 11, 3165 - 3171.
Chemical biology of base-modified nucleic acids
201. Botha, F.; Slavíčková, M.; Pohl, R.; Hocek, M.: "Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides" Org. Biomol. Chem. 2016, 14, 10018 - 10022.
Chemical biology of base-modified nucleic acids
200. Sabat, N.; Poštová Slavětínská L.; Klepetářová, B.; Hocek, M.: "C–H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives" J. Org. Chem. 2016, 81, 9507 - 9514.
Chemical biology of base-modified nucleic acids
199. Olszewska, A.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M.: "Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins" Bioconjugate Chem. 2016, 27, 2089 - 2094.
Chemical biology of base-modified nucleic acids
198. Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M.: "6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study" Bioorg. Med. Chem. 2016, 24, 4528 - 4535.
Chemical biology of base-modified nucleic acids
197. Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M.: "Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions" Chem. Sci. 2016, 7, 5775 - 5785.
Chemical biology of base-modified nucleic acids
196. Daňhel, A.; Trošanová, Z.; Balintová, J.; Havran, L.; Hocek, M.; Barek, J.; Fojta, M.: "Voltammetric analysis of 5-(4-Azidophenyl)-2'-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs" Electrochim. Acta 2016, 215, 72 - 83.
Chemical biology of base-modified nucleic acids
195. Perlíková, P.; Rylová, G.; Nauš, P.; Elbert, T.; Tloušťová, E.; Bourderioux, A.; Poštová Slavětínská, L.; Motyka, K.; Doležal, D.; Znojek, P.; Nová, A.; Harvanová, M.; Džubák, P.; Šiller, M.; Hlaváč, J.; Hajdúch, M.; Hocek, M.: "7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action" Mol. Cancer Ther. 2016, 15, 922 – 937.
Chemical biology of base-modified nucleic acids
194. Raindlová, V.; Janoušková, M.; Slavíčková, M.; Perlíková, P.; Boháčová, S.; Milisavljevič, N.; Šanderová, H.; Benda, M.; Barvík, I.; Krásný, L.; Hocek, M.: "Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases" Nucleic Acids Res. 2016, 44, 3000 – 3012.
Chemical biology of base-modified nucleic acids
193. Dadová, J.; Cahová, H.; Hocek, M.: "Polymerase Synthesis of Base-Modified DNA" in K. Nakatani, Y. Tor (eds.), Modified Nucleic Acids, Nucleic Acids and Molecular Biology Series, Vol. 31, Springer 2016, 123 - 144.
Chemical biology of base-modified nucleic acids
192. Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M.: "Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurineBases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions" Synthesis 2016, 48, 1029 – 1045.
Chemical biology of base-modified nucleic acids
191. Kielkowski, P.; Cahová, H.; Pohl, R.; Hocek, M.: "Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases" Bioorg. Med. Chem. 2016, 24, 1268 – 1276.
Chemical biology of base-modified nucleic acids
190. Dziuba, D.; Jurkiewicz, P.; Cebecauer, M.; Hof, M.; Hocek, M.: "A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy" Angew. Chem. Int. Ed. 2016, 55, 174 – 178.
Chemical biology of base-modified nucleic acids
189. Güixens-Gallardo, P.; Hocek, M.; Perlíková, P.: "Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates" Bioorg. Med. Chem. Lett. 2016, 26, 288 – 291.
Chemical biology of base-modified nucleic acids

2015
188. Tokarenko, A.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Synthesis of Benzene and Pyridine 2'-C-Methyl-C-ribonucleosides and -nucleotides" Eur. J. Org. Chem. 2015, 36, 7962 – 7983.
Chemical biology of base-modified nucleic acids
187. Klečka, M.; Poštová Slavětínská, L.; Hocek, M.: "Modification of Pyrrolo[2,3-d]pyrimidines by C–H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases" Eur. J. Org. Chem. 2015, 36, 7943 – 7961.
Chemical biology of base-modified nucleic acids
186. Nauš, P.; Caletková, O.; Perlíková, P.; Poštová Slavětínská, L.; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides" Bioorg. Med. Chem. 2015, 23, 7422 – 7438.
Chemical biology of base-modified nucleic acids
185. Sabat, N.; Poštová Slavětínská, L.; Hocek, M.: "Ir-catalyzed C–H silylations of phenyldeazapurines" Tetrahedron Lett. 2015, 49, 6860 – 6862.
Chemical biology of base-modified nucleic acids
184. Olszewska, A.; Daďová, J.; Mačková, M.; Hocek, M.: "Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases" Bioorg. Med. Chem. 2015, 21, 6885 – 6890.
Chemical biology of base-modified nucleic acids
183. Daďová, J.; Vrábel, M.; Adámik, M.; Brázdová, M.; Pohl, R.; Fojta, M.; Hocek, M.: "Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA–Protein Cross-Linking" Chem. Eur. J. 2015, 21, 16091 – 16102.
Chemical biology of base-modified nucleic acids
182. Mačková, M.; Boháčová, S.; Perlíková, P.; Poštová Slavětínská, L.; Hocek, M.: "Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine" ChemBioChem 2015, 16, 2225 – 2236.
Chemical biology of base-modified nucleic acids
181. Downey, A. M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M.: "Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose" Org. Lett. 2015, 17, 4604 – 4607.
Chem
180. Malnuit, V.; Poštová Slavětínská, L.; Nauš, P.; Džubák, P.; Hajdúch, M.; Stolaříková, J.; Snášel, J.; Pichová, I.; Hocek, M.: "2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity" ChemMedChem 2015, 10, 1079 – 1093.
Chemical biology of base-modified nucleic acids
179. Klečka, M.; Slavětínská, L.; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides" Med. Chem. Commun. 2015, 6, 576 – 580.
Chemical biology of base-modified nucleic acids
178. Dziuba, D.; Pohl, R.; Hocek, M.: "Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins" Chem. Commun. 2015, 51, 4880 – 4882.
Chemical biology of base-modified nucleic acids
177. Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction" Bioconjugate Chem. 2015, 26, 361 – 366.
Chemical biology of base-modified nucleic acids
176. Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M.: "Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions" Chem. Sci. 2015, 6, 575 – 587.
Chemical biology of base-modified nucleic acids

2014
175. Simonova, A.; Balintová, J.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: "Methoxyphenol and dihydrobenzofuran as new oxidizable labels for electrochemical detection of DNA" ChemPlusChem 2014, 79, 1703 – 1712.
Chemical biology of base-modified nucleic acids
174. Dziuba, D.; Pohl, R.; Hocek, M.: "Bodipy-labelled nucleoside triphosphates for polymerase synthesis of fluorescent DNA" Bioconjugate Chem. 2014, 25, 1984 – 1995.
Chemical biology of base-modified nucleic acids
173. Sabat, N.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Direct C–H amination and C–H chloroamination of 7-deazapurines" RSC Adv. 2014, 4, 62140 – 62143.
Chemical biology of base-modified nucleic acids
172. Hocek, M.: "Synthesis of Base-Modified 2'-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology" J. Org. Chem 2014, 79, 9914 – 9921.
Chemical biology of base-modified nucleic acids
171. Krömer, M.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Chemoselective synthesis of 4,5-diarylpyrrolo[2,3-d]pyrimidines (6,7-diaryl-7-deazapurines) by consecutive Suzuki and Liebeskind-Srogl cross-couplings" Eur. J. Org. Chem. 2014, 32, 7203 – 7210.
Chemical biology of base-modified nucleic acids
170. Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; Zábranská, H.; Pohl, R.; Konečný, P.; Džubák, P.; Votruba, I.; Hajdúch, M.; Řezáčová, P.; Veverka, V.; Hocek, M.; Pichová, I.: "Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(het)aryl-7-deazaadenine ribonucleosides" J. Med. Chem. 2014, 57, 8268 – 8279.
Chemical biology of base-modified nucleic acids
169. Mačková, M.; Pohl, R.; Hocek, M.: "Polymerase synthesis of DNA bearing vinyl groups in major groove and their cleavage by restriction endonucleases" ChemBioChem 2014, 15, 2306 – 2312.
Chemical biology of base-modified nucleic acids
168. Dhami, K.; Malyshev, D. A.; Ordoukhanian, P.; Kubelka, T.; Hocek, M.; Romesberg, F. E.: "Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet" Nucleic Acids Res. 2014, 42, 10235 – 10244.
Chemical biology of base-modified nucleic acids
167. Kielkowski, P.; Fanfrlík, J.; Hocek, M.: "7-Aryl-7-deazaadenine 2'-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations" Angew. Chem. Int. Ed. 2014, 53, 7552 - 7555.
Chemical biology of base-modified nucleic acids
166. Vaníková, Z.; Hocek, M.: "Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases" Angew. Chem. Int. Ed. 2014, 53, 6734 - 6737.
Chemical biology of base-modified nucleic acids
165. Hocek, M.: "Preparation of Base-Modified DNA by Enzymatic Incorporation of Modified Nucleoside Triphosphates" (in Czech) Chem. Listy 2014, 108, 320 - 325.
164. Čerňová, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: "C-H Trifluormethylations of 1,3-dimethyluracil and reactivity of the products in C-H arylations" Heterocycles 2014, 89, 1159 - 1171.
Chemical biology of base-modified nucleic acids
163. Danhel, A.; Raindlova, V.; Havran, L.; Barek, J.; Hocek, M.; Fojta, M.: "Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan" Electrochimica Acta 2014, 129, 348 - 357.
Chemical biology of base-modified nucleic acids
162. Danhel, A.; Raindlova, V.; Havran, L.; Pivonkova, H.; Hocek, M.; Fojta, M.: "Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silversolid amalgam electrode" Electrochimica Acta 2014, 126, 122 - 131.
Chemical biology of base-modified nucleic acids
161. Nauš,P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušťová, E.; Perlíková, P.; Hajdúch, M.; Hocek, M.: "Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides" J. Med. Chem. 2014, 57, 1097 – 1110.
Chemical biology of base-modified nucleic acids

2013
160. Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M.: "6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents" Med. Chem. Commun. 2013, 4, 1497 – 1500.
159. Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: "Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA" J. Org. Chem. 2013, 78, 9627 – 9637.
158. Dadová, J.; Orság, P.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M.: "Vinylsulfonamide and Acrylamide Modification of DNA for Crosslinking with Proteins" Angew. Chem. Int. Ed. 2013, 52, 10515 – 10518.
157. Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: "Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases" Chem. Eur. J. 2013, 19, 12720 – 12731.
156. Tichý, M.; Pohl, R.; Tloušťová, E.; Weber, J.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido [4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2013, 21, 5362-5372.
155. Klečka, M.; Pohl, R.; Čejka, J.; Hocek, M.: "Direct C–H sulfenylation of purines and deazapurines" Org. Biomol. Chem. 2013, 11, 5189-5193.
154. Kubelka, T.; Slavětínská, L.; Eigner, V.; Hocek, M.: "Synthesis of 2,6-disubstituted pyridin-3-yl C-2’-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides" Org. Biomol. Chem. 2013, 11, 4702-4718.
153. Ménová, P.; Raindlová, V.; Hocek, M.: "Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR" Bioconjugate Chem. 2013, 24, 1081-1093.
152. Kielkowski, P.; Brock, N. L.; Dickschat, J. S.; Hocek, M.: "Nucleobase Protection Strategy for Gene Cloning and Expression" ChemBioChem 2013, 14, 801-804.
151. Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and Cytostatic and Antiviral Activities of 2’-Deoxy-2’,2’-difluororibo- and 2’-Deoxy-2’-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines" ChemMedChem 2013, 8, 832-846.
150. Ménová, P.; Cahová, H.; Plucnara, M.; Havran, L.; Fojta, M.; Hocek, M.: "Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling" Chem. Commun. 2013, 49, 4652-4654.
149. Kalachová, L.; Pohl, R.; Bednárová, L.; Fanfrlík, J.; Hocek, M.: "Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations" Org. Biomol. Chem. 2013, 11, 78-89.

2012
148. Riedl, J.; Ménová, P.; Pohl, R.; Orság, P.; Fojta, M.; Hocek, M.: "GFP-like Fluorophores as DNA Labels for Studying DNA-Protein Interactions" J. Org. Chem. 2012, 77, 8287-8293.
147. Tichý, M.; Pohl, R.; Xu, H. Y.; Chen, Y.-L.; Yokokawa, F.; Shi, P.-Y.; Hocek, M.: "Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2012, 20, 6123–6133.
146. Kubelka, T.; Slavětínská, L.; Hocek, M.: "Synthesis of Substituted Benzyl Homo-C-ribonucleosides and -nucleotides as Carba Analogues of Phosphoribosylanthranilate" Eur. J. Org. Chem. 2012, 4969–4981.
145. Riedl, J.; Pohl, R.; Ernsting, N. P.; Orság, P.; Fojta, M.; Hocek, M.: "Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions" Chem. Sci. 2012, 3, 2797–2806.
144. Perlíková, P.; Jornet Martínez, N.; Slavětínská, L.; Hocek, M.: "Synthesis of 2'-deoxy-2'-fluororibo- and 2'-deoxy-2',2'-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines" Tetrahedron 2012, 68, 8300-8310.
143. Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M.: "Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides" Bioorg. Med. Chem. 2012, 20, 5202–5214.
142. Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivoňková, H.; Fojta, M.; Hocek, M.: "Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling" ChemPlusChem 2012, 77, 652–662.
141. Ménová, P.; Hocek, M.: "Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction" Chem. Commun. 2012, 48, 6921–6923.
140. Čerňová, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: "A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions" Synlett 2012, 23, 1305–1308.
139. Raindlová, V.; Pohl, R.; Hocek, M.: "Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination" Chem. Eur. J. 2012, 18, 4080-4087.
138. Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M.: "Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides" Eur. J. Org. Chem. 2012, 1759-1767.
137. Kubelka, T.; Slavětínská, L.; Hocek, M.: "A General Regioselective Approach to 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides" Synthesis 2012, 44, 953-965.
136. Riedl, J.; Pohl, R.; Rulíšek, L.; Hocek, M.: "Synthesis and Photophysical Properties of Biaryl-Substituted Nucleos(t)ides. Polymerase Synthesis of DNA Probes Bearing Solvatochromic and pH-Sensitive Dual Fluorescent and 19F NMR Labels" J. Org. Chem. 2012, 77, 1026-1044.
135. Kalachová, L.; Pohl, R.; Hocek, M.: "Synthesis of nucleoside mono- and triphosphates bearing oligopyridine ligands, their incorporation into DNA and complexation with transition metals" Org. Biomol. Chem. 2012, 10, 49-55.

2011
134. Balintová, J.; Pohl, R.; Horáková, P.; Vidláková, P.; Havran, L.; Fojta, M.; Hocek, M.: "Anthraquinone as a Redox Label for DNA: Synthesis, Enzymatic Incorporation, and Electrochemistry of Anthraquinone-Modified Nucleosides, Nucleotides, and DNA" Chem. Eur. J. 2011, 17, 14063–14073.
133. Hocek, M.; Fojta, M.: "Nucleobase modification as redox DNA labelling for electrochemical detection" Chem. Soc. Rev. 2011, 40, 5802–5814.
132. Kielkowski, P.; Macíčková-Cahová, H.; Pohl, R.; Hocek, M.: "Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases" Angew. Chem. Int. Ed. 2011, 50, 8727 –8730.
131. Štambaský, J.; Kapras, V.; Štefko, M.; Kysilka, O.; Hocek, M.; Malkov, A. V.; Kočovský, P.: "A Modular Approach to Aryl-C-ribonucleosides via the Allylic Substitution and Ring-Closing Metathesis Sequence. A Stereocontrolled Synthesis of All Four α-/β- and D-/L- C-Nucleoside Stereoisomers" J. Org. Chem. 2011, 76, 7781–7803.
130. Štefko, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "General and Modular Synthesis of Isomeric 5-Substituted Pyridin-2-yl and 6-Substituted Pyridin-3-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Hetaryl, Amino, Carbamoyl, and Hydroxy Groups" J. Org. Chem. 2011, 76, 6619–6635.
129. Standara, S.; Bouzková, K.; Straka, M.; Zacharová, Z.; Hocek, M.; Marek, J.; Marek, R.: "Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines" Phys. Chem. Chem. Phys. 2011, 13, 15854–15864.
128. Lund, T. J.; Cavanaugh, N. A.; Joubert, N.; Urban, M.; Patro, J. N.; Hocek, M.; Kuchta, R. D.: "B Family DNA Polymerases Asymmetrically Recognize Pyrimidines and Purines" Biochemistry 2011, 50, 7243-7250.
127. Nečas, D.; Hidasová, D.; Hocek, M.; Kotora, M.: "Modular synthesis of 1-α- and 1-β-(indol-2-yl)-2'-deoxyribose C-nucleosides" Org. Biomol. Chem. 2011, 9, 5934–5937.
126. Fojta, M.; Havran, L.; Pivoňková, H.; Horáková, P.; Hocek, M.: "Redox Labels and Indicators Based on Transition Metals and Organic Electroactive Moieties for Electrochemical Nucleic Acids Sensing" Curr. Org. Chem. 2011, 15, 2936-2949.
125. Bourderioux, A.; Nauš, P.; Perlíková, P.; Pohl, R.; Pichová, I.; Votruba, I.; Džubák, P.; Konečný, P.; Hajdúch, M.; Stray, K.M.; Wang, T.; Ray, A.S.; Feng, J.Y.; Birkus, G.; Cihlar, T.; Hocek, M.: " Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines " J. Med. Chem. 2011 , 54 , 5498–5507.
124. Čerňová, M.; Čerňa, I.; Pohl, R.; Hocek, M.: " Regioselective Direct C-H Arylations of Protected Uracils. Synthesis of 5- and 6-Aryluracil Bases " J. Org. Chem. 2011 , 76 , 5309-5319.
123. Nauš, P.; Perlíková, P.; Pohl, R.; Hocek, M.: " Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2'- C -methylribonucleosides, arabinonucleosides and 2'-deoxy-2'-fluoroarabinonucleosides " Collect. Czech. Chem. Commun. 2011 , 76 , 957-988.
122. Stevens, K.; Claeys, D.D.; Catak, S.; Figaroli, S.; Hocek, M.; Tromp, J.M.; Schürch, S.; Speybroeck, V.; Madder, A.: " Furan-Oxidation-Triggered Inducible DNA Cross-Linking: Acyclic Versus Cyclic Furan-Containing Building Blocks—On the Benefit of Restoring the Cyclic Sugar Backbone " Chem. Eur. J. 2011 , 17 , 6940-6953.
121. Macíčková-Cahová, H.; Pohl, R.; Horáková, P.; Havran, L.; Špaček, J.; Fojta, M.; Hocek, M.: " Alkylsulfanylphenyl Derivatives of Cytosine and 7-Deazaadenine Nucleosides, Nucleotides and Nucleoside Triphosphates: Synthesis, Polymerase Incorporation to DNA and Electrochemical Study " Chem. Eur. J. 2011 , 17 , 5833–5841.
120. Kielkowski, P.; Pohl, R.; Hocek, M.: " Synthesis of Acetylene Linked Double-Nucleobase Nucleos(t)ide Building Blocks and Polymerase Construction of DNA Containing Cytosines in the Major Groove " J. Org. Chem. 2011 , 76 , 3457–3462.
119. Horáková, P.; Macíčková-Cahová, H.; Pivoňková, H.; Špaček, J.; Havran, L.; Hocek, M.; Fojta, M.: " Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl tranferase. Application in electrochemical DNA hybridization and protein-DNA binding assays " Org. Biomol. Chem. 2011 , 9 , 1366 – 1371.
118. Macíčková-Cahová, H.; Pohl, R.; Hocek, M.: " Cleavage of Functionalized DNA Containing 5-Modified Pyrimidines by Type II Restriction Endonucleases " ChemBioChem 2011 , 12 , 431 – 438.
117. Perlíková, P.; Pohl, R.; Votruba, I.; Shih, R.; Birkuš, G.; Cihlář, T.; Hocek, M.: " Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides " Bioorg. Med. Chem. 2011 , 19 , 229-242.

2010
116. Opekar, S.; Turek, P.; Pohl, R.; Klepetářová, B.; Votruba, I.; Hocek, M.; Kotora, M.: " [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with ?,?-Diynes " Heterocycles 2010 , 82 , 895-907.
115. Štefko, M.; Hocek, M.: " Synthesis of Phenol and Pyridone C-Ribo- and 2'-Deoxyribonucleosides by Palladium-Catalyzed Hydroxylations of Haloaryl C-Nucleosides " Synthesis 2010 , 4199–4206.
114. Bárta, J.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: " Modular Synthesis of 5-Substituted Furan-2-yl C-2'-Deoxyribonucleosides and Biaryl Covalent Base-Pair Analogues " Eur. J. Org. Chem. 2010 , 5432–5443.
113. Spáčilová, P.; Nauš, P.; Pohl, R.; Votruba, I.; Snášel, J.; Zábranská, H.; Pichová, I.; Ameral, R.; Birkuš, G.; Cihlář, T.; Hocek, M.: " CycloSal-phosphate Pronucleotides of Cytostatic 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine Kinases " ChemMedChem 2010 , 5 , 1386–1396.
112. Kubelka, T.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: " Synthesis of 2,4-Disubstituted Pyrimidin-5-yl C-2'-Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4-Dichloropyrimidine Nucleosides " Eur. J. Org. Chem. 2010 , 2666–2669.
111. Marek, R.; Křístková, A.; Maliňáková, K.; Toušek, J.; Marek, J.; Hocek, M.; Malkina, O.L.; Malkin, V.G.: " Interpretation of Indirect Nuclear Spin-Spin Couplings in Isomers of Adenine: Novel Approach to Analyze Coupling Electron Deformation Density Using Localized Molecular Orbitals " J. Phys. Chem. A 2010 , 114 , 6689–6700.
110. Standara, S.; Maliňáková, K.; Marek, R.; Marek, J.; Hocek, M.; Vaara, J.; Straka, M.: " Understanding the NMR chemical shifts for 6-halopurines: role of structure, solvent and relativistic effects " Phys. Chem. Chem. Phys. 2010 , 12 , 5126–5139.
109. Čerňa, I.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines " J. Org. Chem. 2010 , 75 , 2302–2308.
108. Hasník, Z.; Pohl, R.; Hocek, M.: " Synthesis of (purin-6-yl)methylphosphonate bases and nucleosides " Tetrahedron Lett. 2010 , 51 , 2464–2466.
107. Raindlová, V; Pohl, R.; Šanda, M.; Hocek, M.: " Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines " Angew. Chem. Int. Ed. 2010 , 49 , 1064–1066.
106. Macíčková-Cahová, H.; Vrábel, M.; Hocek, M.: " Cross-Coupling Modification of Nucleoside Triphosphates, PEX, and PCR Construction of Base-Modified DNA " Curr. Protoc. Chem Biol. 2010 , 2 , 1-14.
105. Ikonen, S.; Macíčková-Cahová, H.; Pohl, R.; Šanda, M.; Hocek, M.: " Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA " Org. Biomol. Chem. 2010 , 8 , 1194-1201.
104. Urban, M.; Joubert, N.; Purse, B.W.; Hocek, M.; Kuchta, R. D.: " Mechanisms by Which Human DNA Primase Chooses To Polymerize a Nucleoside Triphosphate " Biochemistry 2010 , 49 , 727–735.
103. Štefko, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: " A General and Efficient Synthesis of Pyridin-2-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Amino, and Carbamoyl Groups in Position 6 " J. Org. Chem. 2010 , 75 , 442–449.
102. Nauš, P.; Pohl, R.; Votruba, I.; Džubák, P.; Hajdúch, M.; Ameral, R.; Birkus, G.; Wang, T.; Ray, A.S.; Mackman, R.; Cihlar, T.; Hocek, M.: " 6-(Het)aryl-7-Deazapurine Ribonucleosides as Novel Potent Cytostatic Agents " J. Med. Chem. 2010 , 53 , 460–470.
101. Bobula, T.; Hocek, M.; Kotora, M.: " Sonogashira reactions of ?- and ß-1-ethynyl-2-deoxyribosides: synthesis of acetylene-extended C-nucleosides " Tetrahedron 2010 , 66 , 530–536.

2009
100. Macíčková-Cahová, H.; Hocek, M.: " Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases " Nucleic Acids Res. 2009 , 37 , 7612–7622.
99. Štambaský, J.; Hocek, M.; Kočovský, P.: " C-Nucleosides: Synthetic Strategies and Biological Applications " Chem. Rev. 2009 , 109 , 6729–6764.
98. Urban, M.; Joubert, N.; Hocek, M.; Alexander, R. E.; Kuchta, R. D.: " Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase " Biochemistry 2009 , 48 , 10866-10881.
97. Zendlová, L.; Řeha, D.; Hocek, M.; Hobza, P.: " Theoretical Study of the Stability of the DNA Duplexes Modified by a Series of Hydrophobic Base Analogues " Chem. Eur. J. 2009 , 15 , 7601-7610.
96. Čerňová, M.; Pohl, R.; Hocek, M.: " Switching the Regioselectivity of Direct C–H Arylation of 1,3-Dimethyluracil " Eur. J. Org. Chem. 2009 , 3698-3701.
95. Hasník, Z.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Synthesis of (Purin-6-yl)acetates and Their Transformations to 6-(2-Hydroxyethyl)- and 6-(Carbamoylmethyl)purines " Collect. Czech. Chem. Commun. 2009 , 74 , 1035-1059.
94. Riedl, J.; Horáková, P.; Šebest, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: " Tetrathiafulvalene-Labelled Nucleosides and Nucleoside Triphosphates: Synthesis, Electrochemistry and the Scope of Their Polymerase Incorporation into DNA " Eur. J. Org. Chem. 2009 , 3519-3525.
93. Štefko, M.; Pohl, R.; Hocek, M.: " Synthesis of benzamide- C -ribonucleosides by Pd-catalyzed aminocarbonylations " Tetrahedron 2009 , 65 , 4471-4483.
92. Hasník, Z.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Cross-Coupling Reactions of Halopurines with Aryl- and Alkyltrifluoro­borates; The Scope and Limitations in the Synthesis of Modified Purines " Synthesis 2009 , 1309-1317.
91. Klečka, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Direct C–H borylation and C–H arylation of pyrrolo[2,3- d ]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines " Org. Biomol. Chem. 2009 , 7 , 866-868.
90. Vrábel, M.; Horáková, P.; Pivoňková, H.; Kalachova, L.; Černocká, H.; Cahová, H.; Pohl, R.; Šebest, P.; Havran, L.; Hocek, M.; Fojta, M.: " Base-Modified DNA Labeled by [Ru(bpy) 3 ] 2+ and [Os(bpy) 3 ] 2+ Complexes: Construction by Polymerase Incorporation of Modified Nucleoside Triphosphates, Electrochemical and Luminescent Properties, and Applications " Chem. Eur. J. 2009 , 15 , 1144-1154.
89. Kalachova, L.; Pohl, R.; Hocek, M.: " Synthesis of 2'-Deoxyuridine and 2'-Deoxycytidine Nucleosides Bearing Bipyridine and Terpyridine Ligands at Position 5 " Synthesis 2009 , 105-112.

2008
88. Hari, Y.; Hwang, G. T.; Leconte, A. M.; Joubert, N.; Hocek, M.; Romesberg, F. E.: " Optimization of the Pyridyl Nucleobase Scaffold for Polymerase Recognition and Unnatural Base Pair Replication " ChemBioChem 2008 , 9 , 2796-2799.
87. Čerňa, I.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Synthesis of 6,8,9-Tri- and 2,6,8,9-Tetrasubstituted Purines by a Combination of the Suzuki Cross-coupling, N-Arylation, and Direct C-H Arylation Reactions " J. Org. Chem. 2008 , 73 , 9048-9054.
86. Cahová, H.; Pohl, R.; Bednárová, L.; Nováková, K.; Cvačka, J.; Hocek, M.: " Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA " Org. Biomol. Chem. 2008 , 6 , 3657-3660.
85. Kuchař, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines " Tetrahedron 2008 , 64 , 10355-10364.
84. Srnec, M.; Chalupský, J.; Fojta, M.; Zendlová, L.; Havran, L.; Hocek, M.; Kývala, M.; Rulíšek, M.: " Effect of Spin-Orbit Coupling on Reduction Potentials of Octahedral Ruthenium(II/III) and Osmium(II/III) Complexes " J. Am. Chem. Soc. 2008 , 130 , 10947-10954.
83. Vrábel, M.; Pohl, R.; Votruba, I.; Sajadi, M.; Kovalenko, S. A.; Ernsting, N. P.; Hocek, M.: " Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7 " Org. Biomol. Chem. 2008 , 6 , 2852-2860.
82. Nauš, P.; Kuchař, M.; Hocek, M.: " Cytostatic and activiral 6-arylpurine ribonucleosides IX. Synthesis and evaluation of 6-substituted 3-deazapurine ribonuclesides " Collect. Czech. Chem. Commun. 2008 , 73 , 665-678.
81. Hocek, M.; Fojta, M.: " Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids " Org. Biomol. Chem. 2008 , 6 , 2233-2241.
80. Kuchař, M.; Pohl, R.; Klepetářová, B.; Votruba, I.; Hocek, M.: " Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations " Org. Biomol. Chem. 2008 , 6 , 2377-2387.
79. Turek, P.; Hocek, M.; Pohl, R.; Klepetářová, B.; Kotora, M.: " Cobalt-Induced Synthesis of 6-(Pyridin-2-yl)purines by Microwave-Enhanced [2+2+2] Cyclotrimerization " Eur. J. Org. Chem. 2008 , 3335-3343.
78. Joubert, N.; Urban, M.; Pohl, R.; Hocek, M.: " Modular Synthesis of 4-Aryl- and 4-Amino-Substituted Benzene C -2'-Deoxyribonucleosides " Synthesis 2008 , 1918-1932.
77. Bambuch, V.; Pohl, R.; Hocek, M.: " Synthesis of 6-(4,5-Dihydrofuran-2-yl)- and 6-(Tetrahydrofuran-2-yl)purine Bases and Nucleosides " Eur. J. Org. Chem. 2008 , 2783-2788.
76. Bárta, J.; Pohl, R.; Klepetářová, B.; Ernsting, N. P.; Hocek, M.: " Modular Synthesis of 5-Substituted Thiophen-2-yl C -2'-Deoxyribonucleosides " J. Org. Chem. 2008 , 73 , 3798-3806.
75. Novák, P.; Číhalová, S.; Otmar, M.; Hocek, M.; Kotora, M.: " Co- and homocyclotrimerization reactions of protected 1-alkynyl-2-deoxyribofuranose. Synthesis of C -nucleosides, C -di- and C -trisaccharide analogues " Tetrahedron 2008 , 64 , 5200-5207.
74. Šilhár, P.; Hocek, M.; Pohl, R.; Votruba, I.; Shih, I.; Mabery, E.; Mackman, R.: " Synthesis, cytostatic and anti-HCV activity of 6-( N -substituted aminomethyl)-, 6-( O -substituted hydroxymethyl)- and 6-( S -substituted sulfanylmethyl)purine nucleosides " Bioorg. Med. Chem. 2008 , 16 , 2329-2366.
73. Štefko, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: " A Modular Methodology for the Synthesis of 4- and 3-Substituted Benzene and Aniline C-Ribonucleosides " Eur. J. Org. Chem. 2008 , 1689-1704.
72. Cahová, H.; Havran, L.; Brázdilová, P.; Pivoňková, H.; Pohl, R.; Fojta, M.; Hocek, M.: " Aminophenyl- and Nitrophenyl-Labeled Nucleoside Triphosphates: Synthesis, Enzymatic Incorporation, and Electrochemical Detection " Angew. Chem. Int. Ed. 2008 , 47 , 2059–2062.
71. Hasník, Z.; Šilhár, P.; Hocek, M.: " Hydroxymethylations of Aryl Halides by Pd-Catalyzed Cross-Couplings with (Benzoyloxy)methylzinc Iodide – Scope and Limitations of the Reaction " Synlett 2008 , 543–546.
70. Kuchař, M.; Hocek, M.; Pohl, R.; Votruba, I.; Shih, I.; Mabery, E.; Mackman, R.: " Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides " Bioorg. Med. Chem. 2008 , 16 , 1400–1424.

2007
69. Brázdilová, P.; Vrábel, M.; Pohl, R.; Pivoňková, H.; Havran, L.; Hocek, M.; Fojta, M.: " Ferrocenylethynyl Derivatives of Nucleoside Triphosphates: Synthesis, Incorporation, Electrochemistry, and Bioanalytical Applications " Chem. Eur. J. 2007 , 13 , 9527–9533.
68. Čerňa, I.; Pohl, R.; Hocek, M.: " The first direct C–H arylation of purine nucleosides " Chem. Commun. 2007 , 4729-4730.
67. Joubert, N.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Modular and Practical Synthesis of 6-Substituted Pyridin-3-yl C-Nucleosides " J. Org. Chem. 2007 , 72 , 6797-6805.
66. Vrábel, M.; Pohl, R.; Klepetářová, B.; Votruba, I.; Hocek, M.: " Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions " Org. Biomol. Chem. 2007 , 5 , 2849–2857.
65. Hasník, Z.; Šilhár, P.; Hocek, M.: " Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent " Tetrahedron Lett. 2007 , 48 , 5589–5592.
64. Čapek, P.; Cahová, H.; Pohl, R.; Hocek, M.; Gloeckner, C.; Marx, A.: " An Efficient Method for the Construction of Functionalized DNA Bearing Amino Acid Groups through Cross-Coupling Reactions of Nucleoside Triphosphates Followed by Primer Extension or PCR " Chem. Eur. J. 2007 , 13 , 6196–6203.
63. Hocek, M.; Šilhár, P.: " Palladium-Catalyzed Cross-Coupling Reactions in C6 Modifications of Purine Nucleosides " Curr. Protocols Nucleic Acid Chem. (J. Wiley & Sons., Inc.) 2007 , 1.16.
62. Vrábel, M.; Hocek, M.; Havran, L.; Fojta, M.; Votruba, I.; Klepetářová, B.; Pohl, R.; Rulíšek, L.; Zendlová, L.; Hobza, P.; Shih, I.; Mabery, E.; Mackman, R.: " Purines Bearing Phenanthroline or Bipyridine Ligands and Their Ru II Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity " Eur. J. Inorg. Chem. 2007 , 1752-1769.
61. Beckman, J.; Kincaid, K.; Hocek, M.; Spratt, T.; Engels, J.; Cosstick, R.; Kuchta, R. D.: " Human DNA Polymerase ? Uses a Combination of Positive and Negative Selectivity To Polymerize Purine dNTPs with High Fidelity " Biochemistry 2007 , 46 , 448-460.

2006
60. Čerňa, I.; Pohl, R.; Klepetářová, B.; Hocek, M.: " Direct C-H Arylation of Purines: Development of Methodology and Its Use in Regioselective Synthesis of 2,6,8-Trisubstituted Purines " Org. Lett. 2006 , 8 , 5389-5392.
59. Hocek, M.; Šilhár, P.; Pohl, R.: " Cytostatic and activiral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3'-deoxyribonucletides " Collect. Czech. Chem. Commun. 2006 , 71 , 1484-1496.
58. Turek, P.; Novák, P.; Pohl, R.; Hocek, M.; Kotora, M.: " Preparation of Highly Substituted 6-Arylpurine Ribonucleosides by Ni-Catalyzed Cyclotrimerization. Scope of the Reaction " J. Org. Chem. 2006 , 71 , 8978-8981.
57. Kuchař, M.; Pohl, R.; Votruba, I.; Hocek, M.: " Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines " Eur. J. Org. Chem. 2006 , 5083-5098.
56. Čapek, P.; Vrábel, M.; Hasník, Z.; Pohl, R.; Hocek, M.: " Aqueous-Phase Suzuki-Miyaura Cross-Coupling Reactions of Free Halopurine Bases " Synthesis 2006 , 3515-3526.
55. Hocek, M.; Šilhár, P.; Shih, I.; Mabery, E.; Mackman, R.: " Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine L-ribonucleosides " Bioorg. Med. Chem. Lett. 2006 , 16 , 5290–5293.
54. Urban, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: " New Modular and Efficient Approach to 6-Substituted Pyridin-2-yl C-Nucleosides " J. Org. Chem. 2006 , 71 , 7322-7328.
53. Čapek, P.; Pohl, R.; Hocek, M.: " Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines. " Org. Biomol. Chem. 2006 , 4 , 2278-2284.
52. Šilhár, P.; Pohl, R.; Votruba, I.; Klepetářová, B.; Hocek, M.: " Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl- 2-(Hydroxymethyl)purine Bases and Nucleosides " Collect. Czech. Chem. Commun. 2006 , 71 , 788-803.
51. Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: " Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides " Synthesis 2006 , 1848-1852.
50. Novák, P.; Pohl, R.; Kotora, M.; Hocek, M.: " Synthesis of C-Aryldeoxyribosides by [2 + 2 + 2]-Cyclotrimerization Catalyzed by Rh, Ni, Co, and Ru Complexes " Org. Lett. 2006 , 8 , 2051-2054.
49. Řeha, D.; Hocek, M.; Hobza, P.: " Exceptional Thermodynamic Stability of DNA Duplexes Modified by Nonpolar Base Analogues Is due to Increased Stacking Interactions and Favorable Solvation: Correlated Ab Initio Calculations and Molecular Dynamics Simulations " Chem. Eur. J. 2006 , 12 , 3587-3595.

2005
48. Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: " Synthesis of 2-Substituted 6-(Hydroxymethyl)Purine Bases and Nucleosides " Collect. Czech. Chem. Commun. 2005 , 70 , 1669-1695.
47. Čapek, P.; Hocek, M.: " Efficient One-Step Synthesis of Optically Pure (Adenin-8-yl)phenylalanine Nucleosides " Synlett 2005 , 3005-3007.
46. Hocek, M.; Pohl, R.; Klepetářová, B.: " A New Modular and Practical Methodology for the Synthesis of 4- or 3-Substituted Phenyl C-Nucleosides " Eur. J. Org. Chem. 2005 , 4525-4528.
45. Čapek, P.; Pohl, R.; Hocek, M.: " Synthesis of Enantiomerically Pure (Purin-6-yl)phenylalanines and Their Nucleosides, a Novel Type of Purine-Amino Acid Conjugates " J. Org. Chem. 2005 , 70 , 8001-8008.
44. Hocek, M.; Nauš, P.; Pohl, R.; Votruba, I.; Furman, P. A.; Tharnish, P. M.; Otto, M. J.: " Cytostatic 6-Arylpurine Nucleosides. 6. SAR in Anti-HCV and Cytostatic Activity of Extended Series of 6-Hetarylpurine Ribonucleosides " J. Med. Chem. 2005 , 48 , 5869-5873.
43. Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: " The First Synthesis and Cytostatic Activity of Novel 6-(Fluoromethyl)purine Bases and Nucleosides " Org. Biomol. Chem. 2005 , 3 , 3001-3007.
42. Hocek, M.; Pohl, R.; Císařová, I.: " Highly Methylated Purines and Purinium Salts as Analogues of Heteromines " Eur. J. Org. Chem. 2005 , 3026-3030.
41. Turek, P.; Kotora, M.; Hocek, M.; Votruba, I.: " Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes " Collect. Czech. Chem. Commun. 2005 , 70 , 339-349.

2004
40. Turek, P.; Kotora, M.; Tišlerová, I.; Hocek, M.; Votruba, I.; Císařová, I.: " Cocyclotrimerization of 6-Alkynylpurines with α,ω-Diynes as a Novel Approach to Biologically Active 6-Arylpurines " J. Org. Chem. 2004 , 69 , 9224-9233.
39. Hocek, M.; Pohl, R.: " Regioselectivity in Cross-Coupling Reactions of 2,6,8-Trichloro-9-(tetrahydropyran-2-yl)purine: Synthesis of 2,6,8-Trisubstituted Purine Bases " Synthesis 2004 , 2869-2876.
38. Čapek, P.; Pohl, R.; Hocek, M.: " A Facile and Efficient Synthesis of (Purin-6-yl)alanines " J. Org. Chem. 2004 , 69 , 7985-7988.
37. Nauš, P.; Votruba, I.; Hocek, M.: " Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides " Collect. Czech. Chem. Commun. 2004 , 69 , 1955-1970.
36. Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: " Facile and Efficient Synthesis of 6-(Hydroxymethyl)purines " Org. Lett. 2004 , 6 , 3225-3228.
35. Sečkářová, P.; Marek, R.; Maliňáková, K.; Kolehmainen, E.; Hocková, D.; Hocek, M.; Sklenář, V.: " Direct Determination of Tautomerism in Purine Derivatives by Low-Temperature NMR Spectroscopy " Tetrahedron Lett. 2004 , 45 , 6259-6263.
34. Hocek, M.: " Synthesis of Protected (Purin-6-yl)glycines via Pd-Catalyzed ?-Arylation of Ethyl N-(Diphenylmethylidene)glycinate with 6-Iodopurines " Heterocycles 2004 , 63 , 1673-1677.
33. Hocek, M.; Hocková, D.; Dvořáková, D.: " Dichotomy in Regioselective Cross-Coupling Reactions of 6,8-Dichloropurines with Phenylboronic Acid and Methylmagnesium Chloride: Synthesis of 6,8-Disubstituted Purines " Synthesis 2004 , 889-894.
32. Hocek, M.; Štěpnička, P.; Ludvík, J.; Císařová, I.; Votruba, I.; Řeha, D.; Hobza, P.: " Ferrocene-Modified Purines as Potential Electrochemical Markers: Synthesis, Crystal Structures, Electrochemistry and Cytostatic Activity of (Ferrocenylethynyl)- and (Ferrocenylethyl)purines " Chem. Eur. J. 2004 , 10 , 2058-2066.

2003
31. Hocek, M.: " C-C and C-X Bond Formation by Cross-coupling Reactions Catalyzed by Transition Metal Complexes (in Czech) " Chem. Listy 2003 , 97 , 1145-1150.
30. Hocek, M.; Dvořák, D.; Havelková, M.: " Covalent Analogues of Nucleobase-Pairs " Nucleosides, Nucleotides Nucleic Acids 2003 , 22 , 775-777.
29. Hocek, M.; Dvořáková, H.: " An Efficient Synthesis of 2-Substituted 6-Methylpurine Bases and Nucleosides by Fe- or Pd-Catalyzed Cross-Coupling Reactions of 2,6-Dichloropurines " J. Org. Chem. 2003 , 68 , 5773-5776.
28. Hocek, M.; Hocková, D.; Štambaský, J.: " Cytostatic 6-Arylpurine Nucleosides V. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides " Collect. Czech. Chem. Commun. 2003 , 68 , 837-848.
27. Turek, P.; Kotora, M.; Hocek, M.; Císařová, I.: " [2+2+2]-Co-cyclotrimerization of 6-Alkynylpurines with Diynes: a Method for Preparation 6-Arylpurines " Tetrahedron Lett. 2003 , 44 , 785-788.
26. Hocek, M.; Votruba, I.; Dvořáková, H.: " Synthesis of Carba-Analogues of Myoseverine by Regioselective Cross-coupling Reactions of 2,6-Dichloro-9-isopropylpurine " Tetrahedron 2003 , 59 , 607-611.
25. Hocek, M.: " Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal- or Organometallics-Mediated C-C Bond Forming Reactions " Eur. J. Org. Chem . 2003 , 245-254.

2002
24. Hocek, M.; Dvořáková, H.; Císařová, I.: " Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected By Diverse Types of Acyclic Carbon Linkages " Collect. Czech. Chem. Commun. 2002 , 67 , 1560-1578.
23. Hocek, M.; Starý, I.; Stará, I. G.; Dvořáková, H.: " Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of trisubstituted benzenes bearing purine and/or pyrimidine rings by cyclotrimerization of 6-ethynylpurines and/or 5-ethynyl-1,3-dimethyluracil " Collect. Czech. Chem. Commun. 2002 , 67 , 1223-1235.
22. Havelková, M.; Dvořák, D.; Hocek, M. " Covalent Analogues of DNA Base-Pairs and Triplets III. Synthesis of 1,4- and 1,3-bis(purin-6-yl)benzenes and 1-(1,3-dimethyluracil-5-yl)-3 or 4-(purin-9-yl)benzenes " Tetrahedron 2002 , 58 , 7431-7435.
21. Hocek, M.; Holý, A.; Dvořáková, H.: " Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides " Collect. Czech. Chem. Commun. 2002 , 67 , 325-335.
20. Hocek, M.; Votruba, I.: " Covalent Analogues of DNA Base-Pairs and Triplets II. Synthesis and Cytostatic Activity of is(purin-6-yl)acetylenes, -diacetylenes and Related Compounds " Bioorg. Med. Chem. Lett. 2002 , 12 , 1055-1057.

2001
19. Havelková, M.; Dvořák, D.; Hocek, M.: " The Suzuki-Miyaura Cross-Coupling Reactions of 2-, 6- or 8-Halopurines with Boronic Acids Leading to 2-, 6- or 8-Aryl- or -Alkenylpurine Derivatives " Synthesis 2001 , 1704-1710.
18. Hocek, M.; Holý, A.; Votruba, I.; Dvořáková, H.: " Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides " Collect. Czech. Chem. Commun. 2001 , 66 , 483-499.
17. Hocek, M.; Starý, I.; Stará, I. G.; Dvořáková, H.: " Cyclotrimerization of 6-ethynylpurines. Synthesis of 1,2,4- and 1,3,5-tris(purin-6-yl)benzenes as novel Hoogsteen-triplet analogues. " Tetrahedron Lett . 2001 , 42 , 519-521.

2000
16. Hocek, M.; Holý, A.; Votruba, I.; Dvořáková, H.: " Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-ß-D- erythro- pentofuranosyl)-, 9-(5-Deoxy-ß-D-ribofuranosyl)- and 9-(2,3-dihydroxypropyl)-6-phenylpurines " Collect. Czech. Chem. Commun. 2000 , 65 , 1683-1697.
15. Hocek, M.: "Synthesis and Biological Activity of 2- and 6- C -Substituted Purine Bases, Nuceosides and Acyclic Nucleotide Analogues - Alfred Bader Award Lecture (in Czech)" Chem. Listy 2000 , 94 , 978-982.
14. Česnek, M; Hocek, M; Holý, A.: " Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6- C -Substituted Purines via Cross-Coupling Reactions of 2-Amino-9-[2-(diisopropoxyphosphorylmethoxy)-ethyl]-6-halopurines with Diverse Organometallic Reagents " Collect. Czech. Chem. Commun. 2000 , 65 , 1357-1373.
13. Hocek, M.; Holý, A.; Votruba, I.; Dvořáková, H.: " Synthesis and Cytostatic Activity of Substituted 6-Phenylpurine Bases and Nucleosides: Application of the Suzuki-Miyaura Cross-Coupling Reactions of 6-Chloropurine Derivatives with Phenylboronic Acids " J. Med. Chem . 2000 , 43 , 1817-1825.

1999
12. Hocková, D.; Hocek, M.; Dvořáková, H.; Votruba, I.:" Synthesis and Cytostatic Activity of Nucleosides and Acyclic Nucleoside Analogues Derived from 6-(Trifluoromethyl)purines " Tetrahedron 1999 , 55 , 11109-11118.
11. Havelková, M.; Hocek, M.; Česnek, M.; Dvořák, D.: " The Suzuki-Miyaura Cross-Coupling Reactions of 6-Halopurines with Boronic Acids Leading to 6-Aryl and 6-Alkenylpurines " Synlett 1999 , 1145-1147.
10. Hocek, M.; Holý, A.: ” Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues " Collect. Czech. Chem. Commun. 1999 , 64 , 229-241.

1997
9. Hocek, M.; Masojídková, M.; Holý, A.: " Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents " Collect. Czech. Chem. Commun. 1997 , 62 , 136-146.
8. Hocek, M.; Masojídková, M.; Holý, A.: " Synthesis of Acyclic Nucleotide Analogues Derived from N -Substituted 6-(1-Aminoethyl)purines via 6-Acetylpurine Derivatives " Tetrahedron 1997 , 53 , 2291-2302.

1996
7. Hocek, M.; Masojídková, M.; Holý, A.; Andrei, G.; Snoeck, R.; Balzarini, J.; De Clercq, E.: " Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines " Collect. Czech. Chem. Commun. 1996 , 61 , 1525-1537.
6. Hocek, M.; Holý, A.: "Acyclic Nucleotide Analogues Derived from 6-(1-Aminoalkyl)purines" Collect. Czech. Chem. Commun. 1996 , 61 (Special Issue) , S55-S58.

1995
5. Hocek, M.; Holý, A: " A Facile Synthesis of 6-Cyanopurines " Collect. Czech. Chem. Commun. 1995 , 60 , 1386-1389.
4. Hocek, M.; Masojídková, M.; Holý, A: " Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl)adenine and 2-(Aminomethyl)hypoxanthine " Collect. Czech. Chem. Commun. 1995 , 60 , 875-882.

1994
3. Hocek, M. ;Masojídková, M.; Holý, A: " A Facile Synthesis of 2-(Aminomethyl)Purines " Synthesis 1994 , 1401-1402.
2. Böhm, S.; Hocek, M.; Němeček, J.; Havlíček, V.; Kuthan, J.: " Preparation snd Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4,6-tetraaryl-1,4-dihydropyridines ." Collect. Czech. Chem. Commun. 1994 , 59 , 1105-1114.
1. Böhm, S.; Hocek, M.; Nešpůrek, S.; Kuthan, J.: " Photocoloration of 2,4,4,6-Tetraaryl-1,4-dihydroppyridines; a Semiempirical Quantum Chemical Study. " Collect. Czech. Chem. Commun. 1994 , 59 , 262-272.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic
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