Dr. Marta Gargantilla López
phone: +420 220 183 343, +34 628 51 71 78
Born 7. 8. 1992 in Madrid, Spain.
Scientific CV:
2010-2015 undergraduate study, Complutense University of Madrid (UCM), specialization in Organic Chemistry (supervisor Paloma Martínez, PhD)..
2015-2016 graduate study, University of Alcalá de Henares (UAH), Therapeutic Targets in Signaling Pathways, specialization in Medicinal Chemistry (supervisor Ana Castro, PhD).
2015-2017 graduate study, National University of Distance Education (UNED), Chemical Science and Technology, specialization in Organic Chemistry (supervisor Ana Castro, PhD).
2017-2021 PhD. study, Medicinal Chemistry Institute (IQM-CSIC) and Autónoma University of Madrid (UAM), supervisors María Jesús Pérez-Pérez, PhD and Eva María Priego-Crespo, PhD.
2021-2022 Postdoctoral study, Medicinal Chemistry Institute (IQM-CSIC), supervisor María Jesús Pérez-Pérez, PhD.
since 2023 Postdoctoral study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek).
List of publications:
5. | Gargantilla, M.; Persoons, L.; Kauerová, T.; Del Río, N.; Daelemans, D.; Priego, E.-M.; Kollar, P. and Pérez-Pérez, M.-J.: "Hybridization Approach to Identify Salicylanilides as Inhibitors of Tubulin Polymerization and Signal Transducers and Activators of Transcription 3 (STAT3)." Pharmaceuticals. 2022, 15 (7), 835. |
4. | Gargantilla, M.; López-Fernández, J.; Camarasa, M.-J.; Persoons, L.; Daelemans, D.; Priego, E.-M. and Pérez-Pérez, M.-J.: "Inhibition of XPO-1 Mediated Nuclear Export through the Michael-Acceptor Character of Chalcones." Pharmaceuticals. 2021, 14 (11), 1131. |
3. | Bueno, O.; Gargantilla, M.; Estevez-Gallego, J.; Martins, S.; Díaz, J.-F.; Camarasa, M.-J.; Liekens, S.; Pérez-Pérez, M.-J. and Priego, E.-M.: "Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the a-T5 loop." European Journal of Medicinal Chemistry. 2019, 171 (1), 195-208. |
2. | Quaglio, D.; Zhdanovskaya, N.; Tobajas, G.; Cuartas, V.; Balducci, S.; Christodoulou, M.-S.; Fabrizi, G.; Gargantilla, M.; Priego, E.-M.; Carmona-Pestaña, A.; Passarella, D.; Screpanti, I.; Botta, B.; Palermo, R.; Mori, M.; Ghirga, F.; Pérez-Pérez, M.-J.: "Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia." ACS Medicinal Chemistry Letters. 2019, 10 (4), 639-643. |
1. | Bort, A.; Quesada, S.; Ramos-Torres, A.; Gargantilla, M.; Priego, E.-M.; Raynal, S.; Lepifre, F.; Gasalla, J.-M.; Rodríguez-Henche, N.; Castro, A. and Díaz-Laviada, I.: "Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation." Scientific Reports. 2018, 8, 4370. |