Ing. Filip Gracias

e-mail: filip.gracias@uochb.cas.cz
phone: +420 220 183 344


Born 12. 07. 1994 in Karlovy Vary (Czech Republic).

Scientific CV:
2013-2016 undergraduate study, University of Chemistry and Technology Prague, Faculty of Chemical Technology, B. Sc. degree - specialization Drug synthesis and production (supervisor Ing. Tomáš Martinů, Ph.D.)
2016-2018 undergraduate study, University of Chemistry and Technology Prague, Faculty of Chemical Technology, M. Sc. degree - specialization Organic Chemistry (supervisor doc. Tomáš Tobrman, Ph.D.)
since 2018 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Prof. Ing. Michal Hocek, CSc., DSc.)




List of publications:

3.	Pospíšil, Š.; Panattoni, A.; Gracias, F.; Sýkorová, V.; Hausnerová, V. V.; Vítovská, D.; Šanderová, H.; Krásný, L.; Hocek, M.: "Epigenetic Pyrimidine Nucleotides in Competition with Natural dNTPs as Substrates for Diverse DNA Polymerases" ACS Chem. Biol. 2022, 17 (10), 2781-2788.
2.	Gracias, F.; Ruiz-Larrabeiti, O.; Vanková Hausnerová, V.; Pohl, R.; Klepetárová, B.; Sýkorová, V.; Krásný, L.; Hocek, M.: "Homologues of epigenetic pyrimidines: 5-alkyl-, 5-hydroxyalkyl and 5-acyluracil and -cytosine nucleotides: synthesis, enzymatic incorporation into DNA and effect on transcription with bacterial RNA polymerase" RSC Chem. Biol. 2022, 3, 1069-1075.
1.	Gracias, F.; Dvořáková, H.; Martinů, T.: "The Beckmann fragmentation of quadricyclanone oxime" Tetrahedron Lett. 2017, 58, 682-684.