Hosek Research Team
Hosek Research Team
Hocek Research Team

M.Sc. Pedro Güixens-Gallardo, PhD.

Pedro Güixens-Gallardo

e-mail: guixens@uochb.cas.cz
phone: +420 220183344

Born 15. 09. 1989 in Mataró, Barcelona (Spain).

Scientific CV:
2007-2012 undergraduate study, Barcelona University (UB), Faculty of Chemistry, Bc.S. (Hons.) degree - specialization in Chemistry (supervisor Doc. Dr. M. Sarret-Pons)
2012-2013 graduate study, Barcelona University (UB), Faculty of Chemistry, M.Sc. degree - specialization in Organic Chemistry (supervisor Doc. Dr. A. M. Montana-Pedrero)
2014-2020 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Prof. Dr. M. Hocek)
since 2021 Postdoctoral stay, Institute Curie (CNRS) in France, (supervisor Prof. M.P. Teulade-Fichou)

Experience:
summer 2011 Uquifa S.A., Sant Celoni, Barcelona, internship under supervision of Dr. M. Lloris.
summer 2010 Parc Científic de Barcelona (PCB), internship under supervision of Dr. Juan C. Fernández.

List of publications:

6. Matyašovský, J.; Tack, L.; Palágyi, A.; Kuba, M.; Pohl, R.; Kraus, T.; Güixens-Gallardo, P.; Hocek, M.: "Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein–DNA binding" Org. Biomol. Chem. 2021, 19, 9966-9974.
5. Güixens-Gallardo, P.; Hocek, M.: "Acetophenyl-thienyl-aniline-linked nucleotide for construction of solvatochromic fluorescence light-up DNA probes sensing protein-DNA interactions" Chem. Eur. J. 2021, 27, 7090-7093.
4. Güixens-Gallardo, P.; Humpolíèková, J.; Miclea, S. P.; Pohl, R.; Kraus, T.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucloetide probes of hybridization and protein-DNA interactions" Org. Biomol. Chem. 2020, 18, 912-919.
3. Güixens-Gallardo, P.; Zawada, Z.; Matyašovský, J.; Dziuba, D.; Pohl, R.; Kraus, T.; Hocek.: "Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in cellulo Incorporation to DNA, Imaging and Flow Cytometry" Bioconjug. Chem. 2018, 29, 3906 – 3912.
2. Güixens-Gallardo, P.; Hocek, M.; Perlíková, P.: "Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates" Bioorg. Med. Chem. Lett. 2016, 26, 288 – 291.
1. Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction" Bioconjugate Chem. 2015, 26, 361 – 366.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic