Dr. Mgr. Miroslav Kuba

e-mail: miroslav.kuba@uochb.cas.cz
phone: +420 220183344


Born 10.1.1992 in Prešov (Slovak Republic).

Scientific CV:
2011-2014 undergraduate study, Faculty of Science P.J.Šafárik University in Košice, Slovakia, Bc. S. degree - specialization organic chemistry, (supervisor RNDr. Mariana Budovská, PhD.)
2014-2016 undergraduate study, Faculty of Science P.J.Šafárik University in Košice, Slovakia, M. S. degree - specialization organic chemistry, (supervisor RNDr. Mariana Budovská, PhD.)
since 2016 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)


List of publications:

6.	Kuba, M.; Khorosyy, P.; Lepšík, M.; Kužmová, E.; Kodr, D.; Kraus, T.; Hocek, M.; Obermayer-Pietsch, B.; O’Sullivan, C. K.: "Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides" Angew. Chem. Int. Ed. 2023, 62, e202307548.
5.	Kuba, M.; Khorosyy, P.; Lepšík, M.; Kužmová, E.; Kodr, D.; Kraus, T.; Hocek, M.; Obermayer-Pietsch, B.; O’Sullivan, C. K. ; : "Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides" Angew. Chem. Int. Ed. 2023, e202307548.
4.	Kuba, M.; Pohl, R.; Kraus, T. and Hocek, M.: "Nucleotides Bearing Red Viscosity-Sensitive Dimethoxy-Bodipy Fluorophore for Enzymatic Incorporation and DNA Labeling" Bioconjugate Chem. 2023, 34 (1), 133-139.
3.	Matyašovský, J.; Tack, L.; Palágyi, A.; Kuba, M.; Pohl, R.; Kraus, T.; Güixens-Gallardo, P.; Hocek, M.: "Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein–DNA binding" Org. Biomol. Chem. 2021, 19, 9966-9974.
2.	Kuba, M.; Kraus, T.; Pohl. R.; Hocek, M.: "Nucleotide bearing benzylidene-tetrahydroxanthylium near-IR fluorophore for sensing DNA replication, secondary structures and interactions" Chem. Eur. J. 2020, 26, 11950-11954.
1.	Kuba, M.; Pohl, R.; Hocek, M.: "Synthesis of 2'-deoxycytidine and its triphosphate bearing tryptophan-based imidazolinone fluorophore for environment sensitive fluorescent labelling of DNA" Tetrahedron 2018, 74, 6621-6629.