Dr. Denise-Liu’ Gracias Leone, M. Sc.

e-mail: denise.leone@uochb.cas.cz
phone: +420 220 183 344


Born 28.5.1992 in Lanciano (Italy).

Scientific CV:
2011-2017 undergraduate study, University of Studies G. D'Annunzio (Chieti-Pescara), M. Sc. degree - specialization Chemistry and Pharmaceutical Technology with thesis in Applied Medicinal Chemistry (supervisor Prof. Antonio Di Stefano)
2015-2016 internship, Farmacia Anna Maria Marciani, Pharmacist (supervisor Doc. Armando Minutolo)
2015-2016 internship, Ospedale F. Renzetti, Hospital Pharmacist (supervisor Doc. Francesco De Vita)
since 2017 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)

Special training:
2017 Professional qualification as a Pharmacist - University of studies G. D`Annunzio (Chieti-Pescara)



List of publications:

3.	Leone, D.-L.; Pohl, R.; Hubálek, M.; Kaderábková, M.; Krömer, M.; Sýkorová, V.; Hocek, M.: "Glyoxal-Linked Nucleotides and DNA for Bioconjugations and Cross-Linking with Arginine-Containing Peptides and Proteins" Chem. Eur. J. 2022, 28, e202104208.
2.	Leone, D.-L.; Hubálek, M.; Pohl, R.; Sýkorová, V.; Hocek, M.: "1,3-Diketone-Modified Nucleotides and DNA for Cross-Linking with Arginine-Containing Peptides and Proteins" Angew. Chem. Int. Ed. 2021, 60, 17383-17387.
1.	Ivancová, I.; Leone, D.-L.; Hocek, M.: "Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking" Curr. Opin. Chem. Biol. 2019, 52, 136-144.