Hosek Research Team
Hosek Research Team
Hocek Research Team

Ing. Michaela Slavíčková, PhD. (Mačková)

Ing. Michaela Slavíčková, PhD.

e-mail: slavickova@uochb.cas.cz
phone: +420 220183344


Born 7.1.1987 in Jaroměř (Czech Republic).

Scientific CV:
2007-2010 undergraduate study, Prague Institute of Chemical Technology, Bc. S. degree - specialization Chemistry and Chemical technologies (supervizor Ing. Michal Himl, Ph.D.)
2010-2012 undergraduate study, Prague Institute of Chemical Technology, Bc. S. degree - specialization Technical Teacher Training (supervisor Ing. Bohuslav Dušek, CSc.)
2010-2012 undergraduate study, Prague Institute of Chemical Technology, M. S. degree - specialization Organic Chemistry (supervisor doc. Ing. Jan Budka, Ph.D.)
2012-2019 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)


List of publications:
10. Slavíčková, M.; Janoušková, M.; Šimonová, A.; Cahová, H.; Kambová, M.; Šanderová, H.; Krásný, L.; Hocek, M.: "Turning off transcription with bacterial RNA polymerase through CuAAC click reactions of DNA containing 5-ethynyluracil" Chem. Eur. J. 2018, 24, 8311 - 8314.
9. Slavíčková, M.; Pohl, R.; Hocek, M.: "Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA" J. Org. Chem. 2016, 81, 11115 - 11125.
8. Botha, F.; Slavíčková, M.; Pohl, R.; Hocek, M.: "Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides" Org. Biomol. Chem. 2016, 14, 10018 - 10022.
7. Raindlová, V.; Janoušková, M.; Slavíčková, M.; Perlíková, P.; Boháčová, S.; Milisavljevič, N.; Šanderová, H.; Benda, M.; Barvík, I.; Krásný, L.; Hocek, M.: "Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases" Nucleic Acids Res. 2016, 44, 3000 – 3012.
6. Olszewska, A.; Daďová, J.; Mačková, M.; Hocek, M.: "Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases" Bioorg. Med. Chem. 2015, 21, 6885 – 6890.
5. Mačková, M.; Boháčová, S.; Perlíková, P.; Poštová Slavětínská, L.; Hocek, M.: "Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine" ChemBioChem 2015, 16, 2225 – 2236.
4. Mačková, M.; Mikšátko, J.; Budka, J.; Eigner, V.; Cuřínová, P.; Lhoták, P.: "Chiral anion recognition by a ureido-thiacalix[4]arene ligand immobilized in the 1,3-alternate conformation" New J. Chem. 2015, 39, 1382 - 1389.
3. Mačková, M.; Pohl, R.; Hocek, M.: "Polymerase synthesis of DNA bearing vinyl groups in major groove and their cleavage by restriction endonucleases" ChemBioChem 2014, 15, 2306 – 2312.
2. Mačková, M.; Himl, M.; Budka, J.; Pojarová, M.; Císařová, I.; Eigner, V.; Cuřínová, P.; Dvořáková, H.; Lhoták, P.: "Self-assembly of 5,11,17,23-tetranitro-25,26,27,28-tetramethoxythiacalix[4]arene with neutral molecules and its use for anion recognition" Tetrahedron 2013, 69, 1397-1402.
1. Mačková, M.; Himl, M.; Minářová, L.; Lang, J.; Lhoták, P.: "Regioselective deuteration of 25,27-dialkoxycalix[4]arenes" Tetrahedron Lett. 2011, 52, 2543-2546.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic