Hosek Research Team
Hosek Research Team
Hocek Research Team

Dr. Lorena Manzanares

C. Lorena Manzanares-Palenzuela

e-mail: lorenamanpa@gmail.com



Born 10. 11. 1986 in Venezuela.

Scientific CV:
2004-2009 undergraduate study, Santa Maria University in Caracas, Venezuela, Bc. Specialization in Pharmacy
2010-2011 graduate study, Complutense University of Madrid, Spain, M. Sc. Specialization in Pharmaceutical Science
2012-2017 PhD. study, Complutense University of Madrid, Spain, PhD. Specialization in Pharmacy (supervisors Prof. Beatriz Lopez-Ruiz and Maria Jesus Lobo-Castanon)
2017-2018 Scientist, Center for Advanced Functional Nanorobots, University of Chemistry and Technology, Czech Republic
2018-2020 Marie Curie Postdoctoral fellow,
Center for Advanced Functional Nanorobots, University of Chemistry and Technology, Czech Republic
2020 Postdoctoral reseacher,
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)


List of publications:
20. Mulholland, C.; Jestřábová, I.; Sett, A.; Ondruš, M.; Sýkorová, V.; Manzanares, C. L.; Šimoncík, O.; Muller, P. and Hocek, M.: "The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70" Commun. Chem. 2023, 6, 65.
19. M. Sánchez-Paniagua, S. Palenzuela-Bastista, C. L. Manzanares-Palenzuela, B. López-Ruiz.: "Electrochemical genosensor for Klotho detection based on aliphatic and aromatic thiols self-assembled monolayers." Talanta 2020, 212, 120735.
18. C. L. Manzanares-Palenzuela, A. M. Pourrahimi, J. Gonzalez-Julian, Z. Sofer, M. Pykal, M. Otyepka, M. Pumera.: "Interaction of single- and double-stranded DNA with multilayer MXene by fluorescence spectroscopy and molecular dynamics simulations." Chem Sci 2019, 10, 10010.
17. Y. Ying, A. M. Pourrahimi, C. L. Manzanares-Palenzuela, F. Novotny, Z. Sofer, M. Pumera.: "Light-Driven ZnO Brush-Shaped Self-Propelled Micromachines for Nitroaromatic Explosives Decomposition." Small 2019, 1902944.
16. C. L. Manzanares-Palenzuela, S. Hermanova, Z. Sofer, M. Pumera.: "Proteinase-sculptured 3D-printed graphene/polylactic acid electrodes as potential biosensing platforms: towards enzymatic modeling of 3D-printed structures." Nanoscale 2019, 11, 12124 - 12131.
15. M. P. Browne, F. Novotny, C. L. Manzanares Palenzuela, J. Sturala, Z. Sofer, M. Pumera.: "2H and 2H/1T-Transition Metal Dichalcogenide Films Prepared via Powderless Gas Deposition for the Hydrogen Evolution Reaction." ACS Sustain Chem Eng 2019, 7, 16440.
14. A. M. Pourrahimi, K. Villa, C. L. Manzanares-Palenzuela, Y. Ying, Z. Sofer, M. Pumera.: "Catalytic and Light-Driven ZnO/Pt Janus Nano/Micromotors: Switching of Motion Mechanism via Interface Roughness and Defect Tailoring at the Nanoscale." Adv Funct Mater 2019, 29, 1808678.
13. C. L. Manzanares-Palenzuela, A. M. Pourrahimi, Z. Sofer, M. Pumera.: "Mix-and-Read No-Wash Fluorescence DNA Sensing System Using Graphene Oxide: Analytical Performance of Fresh Versus Aged Dispersions." ACS Omega 2019, 4, 1611 - 1616.
12. K. Villa, C. L. Manzanares-Palenzuela, Z. Sofer, S. Matejkova, M. Pumera.: "Metal-Free Visible-Light Photoactivated C3N4 Bubble-Propelled Tubular Micromotors with Inherent Fluorescence and On/Off Capabilities." ACS Nano 2018, 12, 12482 - 12491.
11. M. Sánchez-Paniagua López, C. L. Manzanares-Palenzuela, B. López-Ruiz.: "Biosensors for GMO testing: nearly 25 years of research." Crit Rev Anal Chem 2018, 48, 391 - 405.
10. López-Ruiz, B., Sánchez-Paniagua López, M., Manzanares-Palenzuela, C.L: "‘Sensors’, in Mahgoub, S. E. O. and Nollet, L. M. L. (eds.)" Testing and Analysis of GMO-containing Foods and Feed. Boca Raton: CRC Press pp. 150.
9. C. L. Manzanares-Palenzuela, M. Pumera.: "(Bio)Analytical chemistry enabled by 3D printing: Sensors and biosensors." TrAC, Trends Anal Chem 2018, 103, 110 - 118.
8. C. L. Manzanares-Palenzuela, J. Luxa, Z. Sofer, M. Pumera.: "MoSe2 Dispersed in Stabilizing Surfactant Media: Effect of the Surfactant Type and Concentration on Electron Transfer and Catalytic Properties." ACS Appl Mater Interfaces 2018, 10, 17820 - 17826.
7. C. L. Manzanares-Palenzuela, F. Novotny, P. Krupicka, Z. Sofer, M. Pumera.: "3D-printed graphene/polylactic acid electrodes promise high sensitivity in electroanalysis." Anal Chem 2018, 90, 5753 - 5757.
6. C. L. Manzanares-Palenzuela, J. P. Martin-Clemente, M. J. Lobo-Castañón, B. López-Ruiz.: "Electrochemical detection of magnetically-entrapped DNA sequences from complex samples by multiplexed enzymatic labelling: Application to a transgenic food/feed quantitative survey." Talanta 2017, 164, 261 - 267.
5. B. Martín-Fernández, C. L. Manzanares-Palenzuela, M. Sánchez-Paniagua López, N. de-los-Santos-Álvarez, Beatriz López-Ruiz.: "Electrochemical Genosensors in Food Safety Assessment." Crit Rev Food Sci Nutr. 2017, 57, 2758 - 2774.
4. C. L. Manzanares-Palenzuela, E. G. R. Fernandes, M. J. Lobo-Castañón, B. López-Ruiz, V. Zucolotto.: "Impedance sensing of DNA hybridization onto nanostructured phthalocyanine-modified electrodes." Electrochim Acta 2016, 221, 86 - 95.
3. C. L. Manzanares-Palenzuela, I. Mafra, J. Costa, M. F. Barroso, N. de-los-Santos-Álvarez, C. Delerue-Matos, M. B. P. P. Oliveira, M. J. Lobo-Castañón, B. López-Ruiz.: "Electrochemical magnetoassay coupled to PCR as a quantitative approach to detect the soybean transgenic event GTS40-3-2 in foods." Sensor Actuat B 2016, 222, 1050 - 1057.
2. C. L. Manzanares-Palenzuela, B. Martín-Fernández, M. Sánchez-Paniagua López, B. López-Ruiz.: "Electrochemical genosensors as innovative tools for the detection of genetically modified organisms." TrAC 2015, 66, 19 - 31.
1. C. L. Manzanares-Palenzuela, N. de-los-Santos-Álvarez, M. J. Lobo-Castañón, B. López-Ruiz.: "Multiplex electrochemical DNA platform for femtomolar-level quantification of genetically modified soybean." Biosens and Bioelect 2015, 68, 259 - 265.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic