Ing. Petra Ménová, Ph.D.

e-mail: menova@uochb.cas.cz
phone: +420 220183344


Born 22. 12. 1985 in Kolín (Czech Republic).

Scientific CV:
2005-2008 undergraduate study, Prague Institute of Chemical Technology, Bc. S. degree - specialization Drug Synthesis and Production (supervisor doc. Ing. Radek Cibulka, Ph.D.)
2008-2010 undergraduate study, Prague Institute of Chemical Technology, M. S. degree - specialization Organic Chemistry (supervisor doc. Ing. Radek Cibulka, Ph.D.)
2009 UROP (Undergraduate Research Opportunities Project) participant at Imperial College, London, UK (supervisor Dr. Robert Davies)
2010-2014 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
since 2015 Postdoctoral stay, Max-Planck-Institut für Kolloid und Grenzflächenforschung (supervisor Prof. Dr. Peter H. Seeberger)


List of publications:

15.	Ménová, P.; Vrábel, M.; Cahová, H.; Hocek, M.: "Synthesis of base-modified dNTPs through cross-coupling reactions and their polymerase incorporation to DNA" (Book Chapter), in Non-Natural Nucleic Acids: Methods and Protocols, Methods in Molecular Biology (N. Shank ed.), Humana Press, New York, NY, 2019, vol. 1973, pp. 39-57.
14.	Daďová, J.; Ménová, P.; Hocek, M.: "Jak syntetizovat umělé DNA, navíc s modifikovanými bázemi" Vesmír 2015/2, 94, 90 – 93.
13.	Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M.: "Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction" Bioconjugate Chem. 2015, 26, 361 – 366.
12.	Ménová, P.; Dvořáková, H.; Eigner, V.; Ludvík, J.; Cibulka, R.: "Electron-Deficient Alloxazinium Salts: Efficient Organocatalysts of Mild and Chemoselective Sulfoxidations with Hydrogen Peroxide" Adv. Synth. Catal. 2013, 355, 3451-3462.
11.	Ménová, P.; Raindlová, V.; Hocek, M.: "Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR" Bioconjugate Chem. 2013, 24, 1081-1093.
10.	Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and Cytostatic and Antiviral Activities of 2’-Deoxy-2’,2’-difluororibo- and 2’-Deoxy-2’-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines" ChemMedChem 2013, 8, 832-846.
9.	Ménová, P.; Cahová, H.; Plucnara, M.; Havran, L.; Fojta, M.; Hocek, M.: "Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling" Chem. Commun. 2013, 49, 4652-4654.
8.	Plucnara, M.; Pivoňková, H.; Havran, L.; Hocek, M.; Ménová, P.; Cahová, H.; Balintová, J.; Fojta, M.: Site-specific labeling of nucleotides in DNA strand for possible usage in electrochemical DNA-sensors FEBS J. 2012, 279, 571-5723.
7.	Riedl, J.; Ménová, P.; Pohl, R.; Orság, P.; Fojta, M.; Hocek, M.: "GFP-like Fluorophores as DNA Labels for Studying DNA-Protein Interactions" J. Org. Chem. 2012, 77, 8287-8293.
6.	Ménová, P.; Cibulka, R.: "Insight into the catalytic activity of alloxazinium and isoalloxazinium salts in the oxidations of sulfides and amines with hydrogen peroxide" J. Mol. Catal. A Chem. 2012, 363-364, 362-370.
5.	Ménová, P.; Hocek, M.: "Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction" Chem. Commun. 2012, 48, 6921–6923.
4.	Ménová, P.; Eigner, V.; Čejka, J.; Dvořáková, H.; Šanda, M.; Cibulka, R.: "Synthesis and structural studies of flavin and alloxazine adducts with O-nucleophiles" J. Mol. Structure 2011, 1004, 178–187.
3.	Ménová, P.; Kafka, F.; Dvořáková, H.; Gunnoo, S.; Šanda, M.; Cibulka, R.: "Pyrazinium salts as efficient organocatalysts of mild oxidations with hydrogen peroxide" Adv. Synth. Catal. 2011, 353, 865–870.
2.	Ménová, P.; Eigner, V.; Cibulka, R.; Čejka, J.; Dvořáková, H.: "5-Ethyl-4a-methoxy-1,3-dimethyl-4a,5-dihydrobenzo[g]pteridine-2,4(1H,3H)dione" Acta Cryst. 2009, E65, o1536–o1537.
1.	Cibulka, R.; Baxová, L.; Dvořáková, H.; Hampl, F.; Ménová, P.; Mojr, V.; Plancq, B.; Sayin, S.: "Catalytic effect of alloxazinium and isoalloxazinium salts on oxidation of sulfides with hydrogen peroxide in micellar media" Collect. Czech. Chem. Commun. 2009, 74, 973-993.