Hosek Research Team
Hosek Research Team
Hocek Research Team

Dr. Robert Musiol

Dr. Robert Musiol

e-mail: musiol@uochb.cas.cz
phone: +420 220183344


Born 5. 9. 1976 in Czestochowa (Poland).

Scientific CV:
1997-2001 Undergraduate study at Pedagogical University of Czestochowa, Poland, M. S. degree
2001-2005 Ph.D. study at University of Silesia, Katowice, Poland
2005-2006 Assistent at University of Silesia, Katowice, Poland
2007-2008 Researcher at University of Silesia, Katowice, Poland
2007 study abroad for 5 months LBPA Ecole Normale Superieure du Cachan, Cedex, France
since 2008 Postdoctoral position at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic

List of publications:
17. Musiol, R.; Tabak, D.; Niedbala, H.; Podeszwa, B.; Jampilek, J.; Kralova, K.; Dohnal, J.; Finster, J.; Mencel, A.; Polanski, J.: "Investigating biological activity spectrum for novel quinoline analogues 2: Hydroxyquinolinecarboxamides with photosynthesis-inhibiting activity" Bioorg. Med. Chem. 2008, 106, 4490-4499.
16. Musiol, R.; Jampilek, J.; Kralova, K.; Richardson, D. R.; Kalinowski, D.; Podeszwa, B.; Finster, J.; Niedbala, H.; Palka, A.; Polanski, J.: "Investigating biological activity spectrum for novel quinoline analogues" Bioorg. Med. Chem. 2007, 105, 1280-1288.
15. Podeszwa, B.; Niedbala, H.; Polanski, J.; Musiol, R.; Tabak, D.; Finster, J.; Serafin, K.; Milczarek, M.; Wietrzyk, J.; Boryczka, S.; Mol, W.; Jampilek, J.; Dohnal, J.; Kalinowski, D. S.; Richardson, D. R.: "Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines" Bioorg. Med. Chem. Lett. 2007, 17, 6138-6141.
14. Polanski, J.; Niedbala, H.; Musiol, R.; Podeszwa, B.; Tabak, D.; Palka, A.; Mencel, A.; Mouscadet, J.-F.; Le Bret, M.: "Fragment Based Approach for the Investigation of HIV-1 Integrase Inhibition" Letters in Drug Design and Discovery 2007, 15, 1280-1288.
13. Musiol, R.; Jampilek, J.; Buchta, V.; Niedbala, H.; Podeszwa, B.; Palka, A.; Majerz-Maniecka, K.; Oleksyn, B.; Polanski, J.: "Antifungal properities of New series of quinoline derivatives" Bioorg. Med. Chem. 2006, 14, 3592-3598.
12. Polanski, J.; Niedbala, H.; Musiol, R.; Podeszwa, B.; Tabak, D.; Palka, A.; Mencel, A.; Finster, J.; Mouscadet, J.-F.; Le Bret, M.: "5-Hydroxy-8-nitro-6-quinaldic acid as a novel molecular scaffold for HIV-1 integrase inhibitors" Letters in Drug Design and Discovery 2006, 3, 175-178.
11. Palka, A.; Musiol, R.; Niedbala, H.; Matlengiewicz, M.; Sajewicz, M.; Serafin, K.; Polanski, J.: "HPLC and 13C NMR for the analysis of transamidation in dynamic combinatorial chemistry system" Acta Chromatographica 2006, 17, 315-319.
10. Nycz, J. E.; Musiol, R.: "New approaches to the synthesis of diphosphine dioxides and hypophosphoric acids esters" Heteroatom Chem. 2006, 17, 310-316.
9. Niedbala, H.; Polanski, J.; Gieleciak, R.; Musiol, R.; Tabak, D.; Podeszwa, B.; Bak, A.; Palka, A.; Mouscadet, J. F.; Gasteiger, J.; LeBret, M.: "Comparative molecular surface analysis (CoMSA) for virtual combinatorial library screening of styrylquinoline HIV-1 blocking agents" Comb. Chem. & HTS 2006, 9, 753-770.
8. Musiol, R.; Podeszwa, B.; Niedbala, H.; Finster, J.; Polanski, J.: "An efficient microwave-assisted synthesis of structurally diverse styrylquinolines" Monatsh. Chem. 2006, 137, 1211-1217.
7. Musiol, R.; Tyman-Szram, B.; Polanski, J.: "Microwave assisted heterocyclic chemistry for undergraduate organic laboratory" Journal of Chemical Education 2006, 83, 632.
6. Musiol, R.; Girek, T.: "Inclusion depending mechanism of modification of cyclodextrins with heterocycles" Cent. Eur. J. Chem. 2005, 4, 742-746.
5. Majerz-Maniecka, K. A.; Musiol, R.; Nitek, W.; Oleksyn, B.J.; Polanski, J.: "Intermolecular interactions in the crystal structures of potential HIV-1 integrase inhibitors" Bioorg. Med. Chem. Lett. 2005, 16, 1005-1009.
4. Musiol, R.; Niedbala, H.; Majerz-Maniecka, K. A.; Oleksyn, B.; Polanski, J.: "Synthesis and structure of styrylquinolines" Annals of Polish Chem. Soc. 2005, 1, 118-122.
3. Tyman-Szram, B.; Musiol, R.; Sajewicz, M.; Polanski, J.: "Thin layer chromatography for the determination of the pKa values of organic acids and bases" Journal of Planar Chromatography, Modern TLC 2005, 18, 328.
2. Polanski, J.; Niedbala, H.; Musiol, R.; Tabak, D.; Podeszwa, B.; Gieleciak, R.; Bak, A.; Palka, A.; Magdziarz, T.: "Analogues of the styrylquinoline and styrylquinazoline HIV-1 integrase inhibitors: design and synthetic problems" Acta Poloniae Pharmaceutica, Drug Research 2004, 61, 3-4.
1. Musiol, R.; Widawska, A.; Polanski, J.: "Optimization of the Schiff base synthesis under microwave irradiation" Annals of Polish Chemical Society 2004, 3, 1290.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic