Hocek Research Team

M.Sc. Marek Ondruš, Ph.D.

Marek Ondruš

e-mail: marek.ondrus@uochb.cas.cz
phone: +420 220 183 344, +421 910 615 120

Born 18. 02. 1992 in Žilina, Slovakia.

Scientific CV:
2011-2014 undergraduate study, Comenius University in Bratislava, Faculty of Science, Slovakia, B.Sc. Specialization in Biochemistry.
2014-2016 postgraduate study, Comenius University in Bratislava, Faculty of Science, Slovakia, M.Sc. Specialization in Organic and Bioorganic Chemistry.
since 2016 PhD. Study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek).

List of publications:

5. Mulholland, C.; Jestřábová, I.; Sett, A.; Ondruš, M.; Sýkorová, V.; Manzanares, C. L.; Šimoncík, O.; Muller, P. and Hocek, M.: "The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70" Commun. Chem. 2023, 6, 65.

4. Ondruš, M.; Sýkorová, V.; Hocek, M.: "Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates" Chem. Commun. 2022, 58, 11248-11251.

3. Ondruš, M.; Sýkorová, V.; Bednárová, L.; Pohl, R.; Hocek, M.: "Enzymatic Synthesis of Hypermodified DNA Polymers for Sequence-Specific Display of Four Different Hydrophobic Groups" Nucleic Acids Res. 2020, 48 (21), 11982-11993.

2. Dobiaš, J.; Ondruš, M.; Hlavác, M.; Murár, M.; Kóna, J.; Addová, G.; Bohác, A.: "Medicinal chemistry: an effect of a desolvation penalty of an amide group in the development of kinase inhibitors." Chem. Pap. 2019, 73, 71-84.

1. Dobiaš, J.; Ondruš, M.; Addová, G.; Bohác, A.: "Switchable highly regioselective synthesis of 3,4-dihydroquinoxaline-2(1H)ones from o-phenylenediamines and aroylpyruvates." Beilstein J. Org. Chem. 2017, 13, 1350-1360.

5.	Mulholland, C.; Jestřábová, I.; Sett, A.; Ondruš, M.; Sýkorová, V.; Manzanares, C. L.; Šimoncík, O.; Muller, P. and Hocek, M.: "The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70" Commun. Chem. 2023, 6, 65.
4.	Ondruš, M.; Sýkorová, V.; Hocek, M.: "Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates" Chem. Commun. 2022, 58, 11248-11251.
3.	Ondruš, M.; Sýkorová, V.; Bednárová, L.; Pohl, R.; Hocek, M.: "Enzymatic Synthesis of Hypermodified DNA Polymers for Sequence-Specific Display of Four Different Hydrophobic Groups" Nucleic Acids Res. 2020, 48 (21), 11982-11993.
2.	Dobiaš, J.; Ondruš, M.; Hlavác, M.; Murár, M.; Kóna, J.; Addová, G.; Bohác, A.: "Medicinal chemistry: an effect of a desolvation penalty of an amide group in the development of kinase inhibitors." Chem. Pap. 2019, 73, 71-84.
1.	Dobiaš, J.; Ondruš, M.; Addová, G.; Bohác, A.: "Switchable highly regioselective synthesis of 3,4-dihydroquinoxaline-2(1H)ones from o-phenylenediamines and aroylpyruvates." Beilstein J. Org. Chem. 2017, 13, 1350-1360.