Hocek Research Team

M.Sc. Alessandro Panattoni, PhD.

Alessandro Panattoni, M. Sc.

e-mail: panattoni@uochb.cas.cz
phone: +420 220183343

Born 13.09.1987 in Pontedera (Italy).

Scientific CV:
2006-2011 undergraduate study, Universita’ di Pisa, Bc.S. degree - specialization in Chemistry (supervisor Prof. Adriano Carpita).
2011-2014 undergraduate study, Universita’ di Pisa, M.Sc. degree - specialization in Organic Chemistry (supervisor Prof. Fabio Bellina).
since 2015 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)

List of publications:

7.	Pospíšil, Š.; Panattoni, A.; Gracias, F.; Sýkorová, V.; Hausnerová, V. V.; Vítovská, D.; Šanderová, H.; Krásný, L.; Hocek, M.: "Epigenetic Pyrimidine Nucleotides in Competition with Natural dNTPs as Substrates for Diverse DNA Polymerases" ACS Chem. Biol. 2022, 17 (10), 2781-2788.
6.	Panattoni, A.; El-Sagheer, A. H.; Brown, T.; Kellett, A.; Hocek, M.: "Oxidative DNA Cleavage with Clip-Phenanthroline Triplex Forming Oligonucleotide Hybrids" ChemBioChem 2020, 21, 991-1000.
5.	Lessi, M.; Panattoni, A.; Guglielmero, L.; Minei, P.; Bellina, F.: "Imidazole-Fused Enediynes by Selective C5–C4 Alkynylations of 4,5-Dibromoimidazoles" Synthesis 2019, 51, 933 - 943.
4.	Panattoni, A.; Pohl, R.; Hocek, M.: "Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Post-Synthetic DNA Functionalization through Copper-Catalyzed Alkyne–Azide 1,3-Dipolar Cycloaddition" Org. Lett. 2018, 20, 3962 - 3965.
3.	Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M.: "5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs" ACS Chem. Biol. 2016, 11, 3165 - 3171.
2.	Barone, V.; Bellina, F.; Biczysko, M.; Bloino, J.; Fornaro, T.; Latouche, C.; Lessi, M.; Marianetti, G.; Minei, P.; Panattoni, A.; Pucci, A. "Toward the design of alkynylimidazole fluorophores: computational and experimental characterization of spectroscopic features in solution and in poly(methyl methacrylate)" Phys. Chem. Chem. Phys. 2015, 17, 26710 - 26723.
1.	Bellina, F.; Lessi, M.; Marianetti, G.; Panattoni, A. "Highly regioselective C-5 Alkynylation of Imidazoles by One-pot Sequential Bromination and Sonogashira Cross Coupling" Tetrahedron Lett. 2015, 56, 3855 – 3857.