Hosek Research Team
Hosek Research Team
Hocek Research Team

Ing. Veronika Sýkorová, Ph.D. (Raindlová)

Ing. Veronika Sýkorová

e-mail: veronika.sykorova@uochb.cas.cz
phone: +420 220183399


Born 15. 8. 1983 in Jeseník (Czech Republic).

Scientific CV:
2003-2008 undergraduate study, Prague Institute of Chemical Technology, M. S. degree - specialization organic chemistry (supervisor Ing. Miroslav Dudič, PhD.)
2008-2013 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
2013-2015 Maternity Leave
since 2015 Postdoctoral stay (supervisor Dr. M. Hocek)



List of publications:
10. Krömer, M.; Bártová, K.; Raindlová, V.; Hocek, M.: "Synthesis of dihydroxyalkynyl and dihydroxyalkyl nucleotides as building blocks or precursors for introduction of diol or aldehyde functions to DNA for bioconjugations" Chem. Eur. J. 2018, 24, 11890-11894.
9. Havranová-Vidláková, P.; Špaček, J.; Vítová, L.; Hermanová, M.; Daďová, J.; Raindlová, V.; Hocek, M.; Fojta, M.; Havran, L.: "Butylacrylate-nucleobase Conjugates as Targets for Two-step Redox Labeling of DNA with an Osmium Tetroxide Complex" Electroanalysis 2018, 30, 371 - 377.
8. Raindlová, V.; Janoušková, M.; Slavíčková, M.; Perlíková, P.; Boháčová, S.; Milisavljevič, N.; Šanderová, H.; Benda, M.; Barvík, I.; Krásný, L.; Hocek, M.: "Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases" Nucleic Acids Res. 2016, 44, 3000 – 3012.
7. Danhel, A.; Raindlova, V.; Havran, L.; Barek, J.; Hocek, M.; Fojta, M.: "Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan" Electrochimica Acta 2014, 129, 348 - 357.
6. Danhel, A.; Raindlova, V.; Havran, L.; Pivonkova, H.; Hocek, M.; Fojta, M.: "Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silversolid amalgam electrode" Electrochimica Acta 2014, 126, 122 - 131.
5. Ménová, P.; Raindlová, V.; Hocek, M.: "Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR" Bioconjugate Chem. 2013, 24, 1081-1093.
4. Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and Cytostatic and Antiviral Activities of 2’-Deoxy-2’,2’-difluororibo- and 2’-Deoxy-2’-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines" ChemMedChem 2013, 8, 832-846.
3. Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivoňková, H.; Fojta, M.; Hocek, M.: "Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling" ChemPlusChem 2012, 77, 652–662.
2. Raindlová, V.; Pohl, R.; Hocek, M.: "Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination" Chem. Eur. J. 2012, 18, 4080-4087.
1. Raindlová, V; Pohl, R.; Šanda, M.; Hocek, M.: "Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines" Angew. Chem. Int. Ed. 2010, 49, 1064–1066.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic