Hosek Research Team
Hosek Research Team
Hocek Research Team

M.Sc. Anna Simonova, PhD.

Dr. Anna Simonova

e-mail: simonova@uochb.cas.cz
phone: +420 220183344


Born 18.5.1990 in Tambov (Russia).

Scientific CV:
2007-2012 undergraduate study, D. Mendeleev University of Chemical Technology Of Russia, Ms. S. degree - specialization nanomaterials (supervisor doc. Ilia Zamilatskov, PhD.)
2012-2018 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
since 2018 Postdoctoral Stay, University of Colorado Boulder (supervisor prof. M. H. Caruthers)



List of publications:
11. Ortiz, M.; Jauset-Rubio, M.; Kodr, D.; Simonova, A.; Hocek, M.; O´Sullivan, C. K.: "Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms" Biosens. Bioelectron. 2021, 198, 113825.
10. Ortiz, M.; Jauset-Rubio, M.; Skouridou, V.; Machado, D.; Viveiros, M.; Clark, T. G.; Simonova, A.; Kodr, D.; Hocek, M.; O´Sullivan, C. K.: "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked RedoxLabeled Nucleotides" ACS Sens. 2021, 6, 4398-4407.
9. Kodr, D.; Yenice, C. P.; Simonova, A.; Saftic, D. P.; Pohl, R.; Sýkorová, V.; Ortiz, M.; Havran, L.; Fojta, M.; Lesnikowski, Z. J.; O’Sullivan, C. K.; Hocek, M.: "Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing" J. Am. Chem. Soc. 2021, 143 (18), 7124-7134.
8. Magrińá, I.; Ortiz, M.; Simonova, A.; Hocek, M.; O'Sullivan, C. K.; Forster, R. J.: "Ferrocene Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics" Langmuir 2021, 37 (11), 3359-3369.
7. Simonova, A.; Magriná, I.; Sýkorová, V.; Pohl, R.; Ortiz, M.; Havran, L.; Fojta, M.; O'Sullivan, C. K.; Hocek, M.: "Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labelling and Coding of Nucleotides and DNA" Chem. Eur. J. 2020, 26, 1286-1291.
6. Magriná, I.; Jauset-Rubio, M.; Ortiz, M.; Tomaso, H.; Simonova, A.; Hocek, M.; O'Sullivan, C. K.: "Duplex electrochemical DNA sensor to detect B.anthracis CAP and PAG DNA targets based on the incorporation of tailed primers and ferrocene labelled dATP" ACS Omega 2019, 4, 21900-21908.
5. Magriná, I.; Toldra, A.; Campas, M.; Ortiz, M.; Simonova, A.; Katakis, I.; Hocek, M.; O'Sullivan, C. K.: "Electrochemical genosensor for the direct detection of tailed PCR amplicons incorporating ferrocene labelled dATP" Biosens. Bioelectron. 2019, 134, 76-82.
4. Daňhel, A.; Trošanová, Z.; Balintová, J.; Simonova, A.; Pospíšil, L.; Cvačka, J.; Hocek, M.; Fojta, M.: "Electrochemical reduction of azidophenyl-deoxynucleoside conjugates at mercury surface" Electrochim. Acta 2018, 259, 377 - 385.
3. Balintová, J.; Simonova, A.; Białek-Pietras, M.; Olejniczak, A.; Lesnikowski, Z. J.; Hocek, M.: "Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA" Bioorg. Med. Chem. Lett. 2017, 27, 4786 - 4788.
2. Simonova, A.; Havran, L.; Pohl, R.; Fojta, M.; Hocek, M.: "Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA" Org. Biomol. Chem. 2017, 15, 6984 – 6996.
1. Simonova, A.; Balintová, J.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: "Methoxyphenol and dihydrobenzofuran as new oxidizable labels for electrochemical detection of DNA" ChemPlusChem 2014, 79, 1703 – 1712.
© Michal Hocek
Institute of Organic Chemistry and Biochemistry
Academy of Sciences of the Czech Republic