Hocek Research Team

Sabina Smoleń, M.Sc., PhD.

e-mail: sabina.smolen@uochb.cas.cz
phone: +420 220183343

Born 15.11.1985 in Lubliniec (Poland).

Scientific CV:
2004-2009 undergraduate study, Jagiellonian University - Faculty of Chemistry, Cracow, Poland, M. Sc. degree - specialization organic chemistry, (supervisor Dr. D. Cież)
2011-2012 postgraduate studies in forensic sciences, University of Warsaw - Center of Forensic Science
2009-2013 PhD study, Institute of Organic Chemistry PAS, (supervisor Dr. D. Gryko)
2014 Postdoctoral position, Institute of Organic Chemistry PAS
2015-2016 Posdoctoral position, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)

List of publications:

13.	Malnuit, V.; Smoleń, S.; Tichý, M.; Poštová Slavětínská, L.; Hocek, M.: "Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine" Eur. J. Org. Chem. 2019, 5409-5423.
12.	Tokarenko, A.; Lišková, B.; Smoleń, S.; Táborská, N.; Tichý, M.; Gurská, S.; Perlíková, P.; Frydrych, I.; Tloušťová, E.; Znojek, P.; Mertlíková-Keiserová, H.; Poštová Slavětínská, L.; Pohl, R.; Klepetářová, B.; Khalid, N.; Wenren, Y.; Laposa, R. R.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides" J. Med. Chem. 2018, 61, 9347-9359.
11.	Tichý, M.; Smoleń, S.; Deingruber, T.; Džubák, P.; Pohl, R.; Poštová Slavětínská, L.; Hajdúch, M.; Hocek, M.: "Thienopyrrolo[2, 3-d]pyrimidines, New Tricyclic Nucleobase Analogues: Synthesis and Biological Activities" ChemistrySelect 2018, 3, 9144-9149.
10.	Sabat, N.; Smoleń, S.; Nauš, P.; Perlíková, P.; Cebová, M.; Poštová Slavětínská, L.; Hocek, M.: "Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines)" Synthesis 2017, 49, 4623 - 4650.
9.	Tichý, M.; Smoleń, S.; Tloušťová, E.; Pohl, R.; Oždian, T.; Hejtmánková, K.; Lišková, B.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides" J. Med. Chem. 2017, 60, 2411 - 2424.
8.	Walaszek, D. J.; Rybicka-Jasińska, K.; Smoleń, S.; Karczewski, M.; Gryko, D.: "Mechanistic Insights into Enantioselective C-H Photooxygenation of Aldehydes via Enamine Catalysis" Adv. Synth. Catal. 2015, 9, 2061 – 2070.
7.	Smoleń, S.; Walaszek, D. J.; Karczewski, M.; Martin, E.; Gryko, D.: "Towards NO-free Regulation of sGC: Design and Synthesis of trans-AB-porphyrins" Isr. J. Chem. 2015, 56, 156 – 168.
6.	Stasyuk, A. J.; Smoleń, S.; Glodkowska-Mrowka, E.; Brutkowskif, W.; Cyrański, M. K.; Tkachenko, N.; Gryko, D. T. : "Synthesis of Fluorescent Naphthoquinolizines via Intramolecular Houben–Hoesch Reaction" Chem. Asian. J. 2015, 10, 553 – 558.
5.	Nazir, R.; Bourquard, F.; Balčiunas, E.; Smoleń, S.; Gray, D.; Tkachenko, N. V.; Farsari, M.; Gryko, D. T. : "?-Expanded ?,ß-Unsaturated Ketones: Synthesis, Optical Properties, and Two-Photon-Induced Polymerization" ChemPhysChem 2015, 16, 682 – 690.
4.	Pisarek, S.; Maximova, K.; Gryko, D. : "Strategies toward the synthesis of amphiphilic porphyrins" Tetrahedron 2014, 70, 6685 – 6715.
3.	Trytek, M.; Lipke, A.; Majdan, M.; Pisarek, S.; Gryko, D. : "Homo- and Heterogeneous ?-Pinene Photooxidation Using a Protoporphyrin-Derived Amide" Eur. J. Org. Chem. 2013, 9, 1653 – 1658.
2.	Maximova, K.; Pisarek, S.; Gryko, D. : "Practical Protocol for the Conjugation of Various Amino Acids to Protoporphyrin IX" Synthesis 2013, 45, 1099 - 1105.
1.	Pisarek, S.; Bednarski, H.; Gryko, D. : "An Efficient Method for Phosphorylation of Alcohols: Preparation of Porphyrin-Derived Phosphates" Synlett 2012, 23, 2667 – 2671.